Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   ACLV7D_RS01090 Genome accession   NZ_OZ217345
Coordinates   210824..211147 (+) Length   107 a.a.
NCBI ID   WP_112445359.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 205824..216147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS01065 (SMIF22_02060) nagA 205952..207103 (+) 1152 WP_173234892.1 N-acetylglucosamine-6-phosphate deacetylase -
  ACLV7D_RS01070 (SMIF22_02070) - 207266..208324 (+) 1059 WP_000649461.1 zinc-dependent alcohol dehydrogenase family protein -
  ACLV7D_RS01075 (SMIF22_02080) - 208475..208840 (+) 366 WP_045606653.1 DUF1033 family protein -
  ACLV7D_RS01080 (SMIF22_02090) comGA/cglA/cilD 208917..209858 (+) 942 WP_164226419.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLV7D_RS01085 (SMIF22_02100) comGB/cglB 209806..210822 (+) 1017 WP_112445357.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACLV7D_RS01090 (SMIF22_02110) comGC/cglC 210824..211147 (+) 324 WP_112445359.1 comG operon protein ComGC Machinery gene
  ACLV7D_RS01095 (SMIF22_02120) comGD/cglD 211110..211544 (+) 435 WP_164226418.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACLV7D_RS01100 (SMIF22_02130) comGE/cglE 211507..211809 (+) 303 WP_191994109.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACLV7D_RS01105 (SMIF22_02140) comGF/cglF 211772..212233 (+) 462 WP_112445365.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACLV7D_RS01110 (SMIF22_02150) comGG/cglG 212211..212624 (+) 414 WP_112445367.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACLV7D_RS01115 (SMIF22_02160) - 212657..213244 (+) 588 WP_164226417.1 class I SAM-dependent methyltransferase -
  ACLV7D_RS01120 (SMIF22_02170) comYH 213305..214258 (+) 954 WP_218764767.1 class I SAM-dependent methyltransferase Machinery gene
  ACLV7D_RS01125 (SMIF22_02180) - 214308..215498 (+) 1191 WP_218764766.1 acetate kinase -
  ACLV7D_RS01130 (SMIF22_02190) rnpA 215646..216017 (+) 372 WP_112445373.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 11986.14 Da        Isoelectric Point: 9.9097

>NTDB_id=1170333 ACLV7D_RS01090 WP_112445359.1 210824..211147(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis F22]
MKKMMTFLKKVKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITEEQAKAYKEYHAKQNTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=1170333 ACLV7D_RS01090 WP_112445359.1 210824..211147(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis F22]
ATGAAAAAAATGATGACATTCTTGAAAAAAGTGAAAGTGAAGGCTTTCACACTTGTGGAAATGTTGGTGGTCTTGCTCAT
CATCAGCGTGCTTCTCTTGCTCTTTGTACCTAATCTGACCAAACAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAGCTTTATAGCTTGGATAAAAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACAGAAGAACAGGCTAAAGCTTATAAAGAATACCATGCTAAACAAAATACCAGTCAAACCGTTGCAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

99.065

100

0.991

  comGC/cglC Streptococcus mitis SK321

92.233

96.262

0.888

  comGC/cglC Streptococcus pneumoniae Rx1

91.176

95.327

0.869

  comGC/cglC Streptococcus pneumoniae D39

91.176

95.327

0.869

  comGC/cglC Streptococcus pneumoniae R6

91.176

95.327

0.869

  comGC/cglC Streptococcus pneumoniae TIGR4

89.32

96.262

0.86

  comYC Streptococcus gordonii str. Challis substr. CH1

69.524

98.131

0.682

  comYC Streptococcus mutans UA140

69.474

88.785

0.617

  comYC Streptococcus mutans UA159

69.474

88.785

0.617

  comYC Streptococcus suis isolate S10

67.045

82.243

0.551

  comGC Lactococcus lactis subsp. cremoris KW2

55.67

90.654

0.505

  comGC Staphylococcus aureus MW2

51.163

80.374

0.411

  comGC Staphylococcus aureus N315

51.163

80.374

0.411


Multiple sequence alignment