Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ACLV7D_RS01100 Genome accession   NZ_OZ217345
Coordinates   211507..211809 (+) Length   100 a.a.
NCBI ID   WP_191994109.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 206507..216809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS01070 (SMIF22_02070) - 207266..208324 (+) 1059 WP_000649461.1 zinc-dependent alcohol dehydrogenase family protein -
  ACLV7D_RS01075 (SMIF22_02080) - 208475..208840 (+) 366 WP_045606653.1 DUF1033 family protein -
  ACLV7D_RS01080 (SMIF22_02090) comGA/cglA/cilD 208917..209858 (+) 942 WP_164226419.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLV7D_RS01085 (SMIF22_02100) comGB/cglB 209806..210822 (+) 1017 WP_112445357.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACLV7D_RS01090 (SMIF22_02110) comGC/cglC 210824..211147 (+) 324 WP_112445359.1 comG operon protein ComGC Machinery gene
  ACLV7D_RS01095 (SMIF22_02120) comGD/cglD 211110..211544 (+) 435 WP_164226418.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACLV7D_RS01100 (SMIF22_02130) comGE/cglE 211507..211809 (+) 303 WP_191994109.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACLV7D_RS01105 (SMIF22_02140) comGF/cglF 211772..212233 (+) 462 WP_112445365.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACLV7D_RS01110 (SMIF22_02150) comGG/cglG 212211..212624 (+) 414 WP_112445367.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACLV7D_RS01115 (SMIF22_02160) - 212657..213244 (+) 588 WP_164226417.1 class I SAM-dependent methyltransferase -
  ACLV7D_RS01120 (SMIF22_02170) comYH 213305..214258 (+) 954 WP_218764767.1 class I SAM-dependent methyltransferase Machinery gene
  ACLV7D_RS01125 (SMIF22_02180) - 214308..215498 (+) 1191 WP_218764766.1 acetate kinase -
  ACLV7D_RS01130 (SMIF22_02190) rnpA 215646..216017 (+) 372 WP_112445373.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11149.10 Da        Isoelectric Point: 9.7674

>NTDB_id=1170335 ACLV7D_RS01100 WP_191994109.1 211507..211809(+) (comGE/cglE) [Streptococcus mitis isolate S. mitis F22]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVVRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIREP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1170335 ACLV7D_RS01100 WP_191994109.1 211507..211809(+) (comGE/cglE) [Streptococcus mitis isolate S. mitis F22]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTGGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAGAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TTGTGCGTGTCGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAATGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTTTATCATGGTTCAGAACAGTTGTTGGCTATCAGAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

97

100

0.97
  comGE/cglE Streptococcus pneumoniae Rx1

97

100

0.97
  comGE/cglE Streptococcus pneumoniae D39

97

100

0.97
  comGE/cglE Streptococcus pneumoniae R6

97

100

0.97
  comGE/cglE Streptococcus pneumoniae TIGR4

97

100

0.97
  comGE/cglE Streptococcus mitis SK321

96

100

0.96
  comYE Streptococcus mutans UA140

42.222

90

0.38
  comYE Streptococcus mutans UA159

42.222

90

0.38

Multiple sequence alignment