Detailed information NTG1138695

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: DQM55_RS10770
• Genome accession: NZ_LS483364
• Coordinates: 2161757..2162074 (-)
• Length: 105 a.a.
• NCBI ID: WP_002896769.1
• Uniprot ID: F3SKF6
• Organism: Streptococcus sanguinis strain NCTC11086
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2156757..2167074

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM55_RS10735 (NCTC11086_02174)	-	2157141..2157890 (-)	750	WP_172454770.1	CPBP family intramembrane glutamic endopeptidase	-
DQM55_RS10740 (NCTC11086_02175)	-	2158033..2159226 (-)	1194	WP_111676737.1	acetate kinase	-
DQM55_RS10745 (NCTC11086_02176)	comYH	2159263..2160228 (-)	966	WP_111676739.1	class I SAM-dependent methyltransferase	Machinery gene
DQM55_RS10750 (NCTC11086_02177)	comGG	2160310..2160702 (-)	393	WP_002907445.1	competence type IV pilus minor pilin ComGG	-
DQM55_RS10755 (NCTC11086_02178)	comGF/cglF	2160683..2161120 (-)	438	WP_111676741.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM55_RS10760 (NCTC11086_02179)	comGE/cglE	2161104..2161397 (-)	294	WP_111676743.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQM55_RS10765 (NCTC11086_02180)	comYD	2161363..2161797 (-)	435	WP_172454771.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQM55_RS10770 (NCTC11086_02181)	comYC	2161757..2162074 (-)	318	WP_002896769.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM55_RS10775 (NCTC11086_02182)	comYB	2162074..2163108 (-)	1035	WP_269459928.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM55_RS10780 (NCTC11086_02183)	comYA	2163038..2163979 (-)	942	WP_111676749.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM55_RS10785 (NCTC11086_02184)	-	2164109..2164489 (-)	381	WP_002903497.1	DUF1033 family protein	-
DQM55_RS10795 (NCTC11086_02185)	-	2164866..2165972 (-)	1107	WP_172454772.1	glycosyl hydrolase family 8	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11400.28 Da
• Isoelectric Point: 9.6959

>NTDB_id=1138695 DQM55_RS10770 WP_002896769.1 2161757..2162074(-) (comYC) [Streptococcus sanguinis strain NCTC11086]
MKKLNTLKVQAFTLVEMLIVLLVISVLLLLFVPNLTKQKDAVSDTGTAAVVKVVESQAELYELKNTNEKASLSKLVSAGN
ISQKQADSYKAYYGKHSGETQAVAN

Nucleotide

• Length: 318 bp

>NTDB_id=1138695 DQM55_RS10770 WP_002896769.1 2161757..2162074(-) (comYC) [Streptococcus sanguinis strain NCTC11086]
ATGAAAAAACTTAATACCTTAAAAGTTCAAGCATTCACCCTTGTGGAAATGCTGATTGTCTTGCTGGTTATCAGCGTACT
CTTGCTGCTCTTTGTGCCTAATCTGACCAAGCAAAAAGATGCTGTTTCAGATACAGGAACGGCAGCGGTGGTCAAGGTAG
TAGAAAGCCAGGCGGAGCTGTATGAGCTTAAGAACACCAATGAAAAGGCTAGCCTGAGCAAGCTAGTCAGCGCAGGAAAT
ATCAGCCAGAAGCAGGCAGATTCATATAAGGCTTACTATGGAAAACACAGTGGCGAAACTCAAGCGGTTGCCAATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (9-30)

3D structure

• AlphaFold DB: F3SKF6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	82.857	100	0.829
comYC	Streptococcus mutans UA159	68.571	100	0.686
comYC	Streptococcus mutans UA140	68.571	100	0.686
comGC/cglC	Streptococcus mitis NCTC 12261	65.138	100	0.676
comGC/cglC	Streptococcus mitis SK321	65.421	100	0.667
comGC/cglC	Streptococcus pneumoniae Rx1	63.551	100	0.648
comGC/cglC	Streptococcus pneumoniae D39	63.551	100	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	63.551	100	0.648
comGC/cglC	Streptococcus pneumoniae R6	63.551	100	0.648
comGC	Lactococcus lactis subsp. cremoris KW2	59	95.238	0.562
comYC	Streptococcus suis isolate S10	61.798	84.762	0.524
comGC	Staphylococcus aureus MW2	43.878	93.333	0.41
comGC	Staphylococcus aureus N315	43.878	93.333	0.41