Detailed information NTG1138692

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: DQM55_RS10755
• Genome accession: NZ_LS483364
• Coordinates: 2160683..2161120 (-)
• Length: 145 a.a.
• NCBI ID: WP_111676741.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain NCTC11086
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2155683..2166120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM55_RS10730 (NCTC11086_02173)	-	2156385..2157023 (-)	639	WP_111676733.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
DQM55_RS10735 (NCTC11086_02174)	-	2157141..2157890 (-)	750	WP_172454770.1	CPBP family intramembrane glutamic endopeptidase	-
DQM55_RS10740 (NCTC11086_02175)	-	2158033..2159226 (-)	1194	WP_111676737.1	acetate kinase	-
DQM55_RS10745 (NCTC11086_02176)	comYH	2159263..2160228 (-)	966	WP_111676739.1	class I SAM-dependent methyltransferase	Machinery gene
DQM55_RS10750 (NCTC11086_02177)	comGG	2160310..2160702 (-)	393	WP_002907445.1	competence type IV pilus minor pilin ComGG	-
DQM55_RS10755 (NCTC11086_02178)	comGF/cglF	2160683..2161120 (-)	438	WP_111676741.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM55_RS10760 (NCTC11086_02179)	comGE/cglE	2161104..2161397 (-)	294	WP_111676743.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQM55_RS10765 (NCTC11086_02180)	comYD	2161363..2161797 (-)	435	WP_172454771.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQM55_RS10770 (NCTC11086_02181)	comYC	2161757..2162074 (-)	318	WP_002896769.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM55_RS10775 (NCTC11086_02182)	comYB	2162074..2163108 (-)	1035	WP_269459928.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM55_RS10780 (NCTC11086_02183)	comYA	2163038..2163979 (-)	942	WP_111676749.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM55_RS10785 (NCTC11086_02184)	-	2164109..2164489 (-)	381	WP_002903497.1	DUF1033 family protein	-
DQM55_RS10795 (NCTC11086_02185)	-	2164866..2165972 (-)	1107	WP_172454772.1	glycosyl hydrolase family 8	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16767.03 Da
• Isoelectric Point: 5.3227

>NTDB_id=1138692 DQM55_RS10755 WP_111676741.1 2160683..2161120(-) (comGF/cglF) [Streptococcus sanguinis strain NCTC11086]
MSKNLKVKAFTLLEALVALLVLSGGILVFQAMTQLLSSELHQQENNQQQEWLLFADQLETELSRSQFDKVEDNKIYIRQD
GRDLALGKSKGDDFRKTDKSGRGYQPMIYGLEAADVRQEGKLVHLHFRFEKGLEREFVYRVEEES

Nucleotide

• Length: 438 bp

>NTDB_id=1138692 DQM55_RS10755 WP_111676741.1 2160683..2161120(-) (comGF/cglF) [Streptococcus sanguinis strain NCTC11086]
GTGTCCAAAAACCTTAAAGTCAAGGCCTTTACTCTCTTGGAGGCTTTAGTAGCCTTGCTGGTTCTCAGTGGTGGAATACT
GGTCTTTCAGGCTATGACCCAGCTCTTATCTTCAGAACTGCATCAGCAGGAGAATAATCAGCAGCAAGAGTGGCTTTTGT
TTGCCGACCAACTGGAGACGGAGCTTTCGCGAAGTCAATTTGACAAGGTTGAAGACAATAAAATCTACATCAGACAGGAT
GGCAGGGACTTGGCCTTGGGTAAATCCAAGGGAGATGATTTCCGTAAAACAGATAAGAGCGGTCGCGGCTACCAGCCGAT
GATTTATGGTTTGGAAGCAGCTGATGTGCGTCAGGAAGGTAAGCTTGTCCATCTTCATTTTCGCTTTGAAAAAGGCTTAG
AGAGGGAGTTCGTCTATCGTGTGGAAGAAGAAAGTTGA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	64.336	98.621	0.634
comGF/cglF	Streptococcus pneumoniae D39	64.336	98.621	0.634
comGF/cglF	Streptococcus pneumoniae R6	64.336	98.621	0.634
comGF/cglF	Streptococcus pneumoniae TIGR4	64.336	98.621	0.634
comGF/cglF	Streptococcus mitis NCTC 12261	62.937	98.621	0.621
comGF/cglF	Streptococcus mitis SK321	62.937	98.621	0.621
comYF	Streptococcus mutans UA159	47.143	96.552	0.455
comYF	Streptococcus mutans UA140	46.429	96.552	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	41.912	93.793	0.393