Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DQM55_RS10745 Genome accession   NZ_LS483364
Coordinates   2159263..2160228 (-) Length   321 a.a.
NCBI ID   WP_111676739.1    Uniprot ID   A0A2X3YJK0
Organism   Streptococcus sanguinis strain NCTC11086     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2154263..2165228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS10725 (NCTC11086_02172) folP 2155237..2156190 (-) 954 WP_111676731.1 dihydropteroate synthase -
  DQM55_RS10730 (NCTC11086_02173) - 2156385..2157023 (-) 639 WP_111676733.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  DQM55_RS10735 (NCTC11086_02174) - 2157141..2157890 (-) 750 WP_172454770.1 CPBP family intramembrane glutamic endopeptidase -
  DQM55_RS10740 (NCTC11086_02175) - 2158033..2159226 (-) 1194 WP_111676737.1 acetate kinase -
  DQM55_RS10745 (NCTC11086_02176) comYH 2159263..2160228 (-) 966 WP_111676739.1 class I SAM-dependent methyltransferase Machinery gene
  DQM55_RS10750 (NCTC11086_02177) comGG 2160310..2160702 (-) 393 WP_002907445.1 competence type IV pilus minor pilin ComGG -
  DQM55_RS10755 (NCTC11086_02178) comGF/cglF 2160683..2161120 (-) 438 WP_111676741.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM55_RS10760 (NCTC11086_02179) comGE/cglE 2161104..2161397 (-) 294 WP_111676743.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM55_RS10765 (NCTC11086_02180) comYD 2161363..2161797 (-) 435 WP_172454771.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM55_RS10770 (NCTC11086_02181) comYC 2161757..2162074 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM55_RS10775 (NCTC11086_02182) comYB 2162074..2163108 (-) 1035 WP_269459928.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM55_RS10780 (NCTC11086_02183) comYA 2163038..2163979 (-) 942 WP_111676749.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM55_RS10785 (NCTC11086_02184) - 2164109..2164489 (-) 381 WP_002903497.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 321 a.a.        Molecular weight: 36717.71 Da        Isoelectric Point: 4.6183

>NTDB_id=1138691 DQM55_RS10745 WP_111676739.1 2159263..2160228(-) (comYH) [Streptococcus sanguinis strain NCTC11086]
MNFEKIEQAYTLILENVQNIQNTLATNFYDALIEQNGIYLDGDTDLQEVLTNDEKIRALHLTKEEWRRVYQFILMKAAQT
EPMQVNHQFTPDTIGFLITFLLDQLAHGEEADVLEIGSGTGNLAETVLNHTQKKIDYLGLELDDLLIDLSASIAEVMNSK
AHFAQGDAVRPQVLKESDIIISDLPVGYYPDDSIASRYEVASPDEHTYAHHLLMEQSLKYLKPGGYAIFLAPNDLLTSAQ
APLLKKWLLAKAQFIAMITLPESIFSSSKHAKTLFVLRKQEANNIQPFIYPLRDLQDHDEMFKFRQSFQNWYKDSEIQTK
F

Nucleotide


Download         Length: 966 bp        

>NTDB_id=1138691 DQM55_RS10745 WP_111676739.1 2159263..2160228(-) (comYH) [Streptococcus sanguinis strain NCTC11086]
ATGAATTTTGAAAAGATAGAACAAGCTTATACTCTGATTCTCGAAAACGTCCAGAATATCCAAAACACTCTGGCGACCAA
TTTTTACGATGCTCTGATTGAGCAGAATGGCATTTACCTAGATGGAGATACTGATTTACAAGAGGTTCTGACCAACGATG
AAAAAATCCGCGCTCTGCATTTGACCAAGGAAGAGTGGCGGAGAGTCTATCAGTTTATCCTGATGAAGGCTGCCCAGACG
GAGCCCATGCAGGTCAATCATCAATTCACACCTGACACAATTGGTTTTCTGATTACTTTCTTATTGGACCAGCTAGCTCA
CGGAGAGGAAGCTGATGTATTAGAAATCGGCAGCGGAACAGGAAATTTGGCTGAGACTGTTCTCAATCATACCCAAAAGA
AGATTGACTACTTAGGTCTGGAGCTAGATGATTTATTAATTGACCTTTCTGCCAGCATTGCAGAGGTTATGAATTCTAAG
GCTCACTTTGCTCAGGGGGATGCAGTTCGCCCTCAGGTTCTGAAAGAGAGTGATATCATTATCAGTGATTTACCGGTTGG
TTATTATCCAGACGACAGTATCGCCTCCCGCTATGAAGTGGCTAGTCCGGATGAGCACACTTATGCCCATCATCTCCTGA
TGGAGCAATCGCTCAAATATCTGAAGCCAGGTGGTTATGCTATATTTCTGGCGCCAAATGATCTCTTGACCAGCGCTCAA
GCTCCTCTGCTGAAAAAATGGCTCCTAGCCAAGGCTCAGTTTATCGCGATGATAACCTTGCCAGAGTCTATTTTCTCAAG
CAGCAAGCATGCCAAAACTCTTTTTGTCTTGAGGAAACAGGAAGCGAATAACATTCAGCCTTTTATCTATCCTCTGCGGG
ATTTGCAGGATCATGATGAAATGTTTAAATTCCGTCAAAGTTTTCAAAACTGGTACAAAGATAGTGAAATTCAAACAAAA
TTTTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3YJK0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

58.413

98.131

0.573
  comYH Streptococcus mutans UA140

58.095

98.131

0.57

Multiple sequence alignment