Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQM55_RS10775 Genome accession   NZ_LS483364
Coordinates   2162074..2163108 (-) Length   344 a.a.
NCBI ID   WP_269459928.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11086     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2157074..2168108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS10735 (NCTC11086_02174) - 2157141..2157890 (-) 750 WP_172454770.1 CPBP family intramembrane glutamic endopeptidase -
  DQM55_RS10740 (NCTC11086_02175) - 2158033..2159226 (-) 1194 WP_111676737.1 acetate kinase -
  DQM55_RS10745 (NCTC11086_02176) comYH 2159263..2160228 (-) 966 WP_111676739.1 class I SAM-dependent methyltransferase Machinery gene
  DQM55_RS10750 (NCTC11086_02177) comGG 2160310..2160702 (-) 393 WP_002907445.1 competence type IV pilus minor pilin ComGG -
  DQM55_RS10755 (NCTC11086_02178) comGF/cglF 2160683..2161120 (-) 438 WP_111676741.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM55_RS10760 (NCTC11086_02179) comGE/cglE 2161104..2161397 (-) 294 WP_111676743.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM55_RS10765 (NCTC11086_02180) comYD 2161363..2161797 (-) 435 WP_172454771.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM55_RS10770 (NCTC11086_02181) comYC 2161757..2162074 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM55_RS10775 (NCTC11086_02182) comYB 2162074..2163108 (-) 1035 WP_269459928.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM55_RS10780 (NCTC11086_02183) comYA 2163038..2163979 (-) 942 WP_111676749.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM55_RS10785 (NCTC11086_02184) - 2164109..2164489 (-) 381 WP_002903497.1 DUF1033 family protein -
  DQM55_RS10795 (NCTC11086_02185) - 2164866..2165972 (-) 1107 WP_172454772.1 glycosyl hydrolase family 8 -
  DQM55_RS10800 (NCTC11086_02186) - 2165981..2167291 (-) 1311 WP_002896777.1 glycosyltransferase family 2 protein -
  DQM55_RS10805 (NCTC11086_02187) - 2167284..2167427 (-) 144 WP_002896778.1 hypothetical protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39023.88 Da        Isoelectric Point: 8.8627

>NTDB_id=1138696 DQM55_RS10775 WP_269459928.1 2162074..2163108(-) (comYB) [Streptococcus sanguinis strain NCTC11086]
MISFLQKDISVLSKGRPKKLSTPKQKKIIELFHNLFSSGFHLAEIVDFLRRSALLEEAYVAEMRAGLSAGQSFSEIVSRL
GFSDSVVTQLSLSELHGNLTLSLGKIEAYLENLSKVKKKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNLATQLIN
HLPQIFLWSSLAWAALVSVALFYYRKSSKIRFFSKLAALPFIGRLVQAYLTAYYAREWGNMIGQGLELSQIFAIMQEQPS
QLFQEIGEDMAAALQGGQGYADKVASYPFFKKELSLMIEYGEVKSKLDSELEVYAEKTWEEFFLRINRAMNFIQPLVFIF
VALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1138696 DQM55_RS10775 WP_269459928.1 2162074..2163108(-) (comYB) [Streptococcus sanguinis strain NCTC11086]
TTGATCAGCTTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAAGCAGAAAAA
GATTATTGAGCTCTTTCATAATCTCTTTAGCAGCGGTTTTCACTTAGCAGAGATTGTAGACTTTCTGAGGCGAAGTGCCT
TGCTGGAGGAGGCTTATGTGGCAGAAATGCGGGCAGGTTTGTCAGCTGGTCAGTCCTTTTCAGAGATTGTCAGTCGACTG
GGATTTTCCGACAGCGTTGTAACCCAGCTGTCCTTATCTGAGCTGCATGGCAATCTGACACTTAGTCTGGGCAAAATTGA
GGCCTATCTGGAAAATCTGTCCAAGGTTAAGAAAAAATTGATAGAGGTAGGAACCTATCCTCTCATGCTGCTGGGCTTTT
TGGTCCTTATCATGCTGGGATTGCGCAACTATCTTCTGCCTCAATTAGACAGCCAGAATCTAGCTACTCAGCTGATTAAT
CACCTGCCTCAGATTTTTTTGTGGAGCAGCCTTGCTTGGGCCGCCTTGGTTTCAGTGGCTCTCTTTTATTATCGAAAGTC
ATCCAAGATTCGTTTTTTCAGCAAACTAGCAGCTCTGCCTTTTATTGGGCGTTTGGTGCAGGCTTACTTGACCGCTTATT
ATGCTCGTGAATGGGGAAATATGATTGGTCAGGGCCTGGAATTGAGTCAGATTTTTGCGATTATGCAGGAGCAGCCTTCC
CAGCTCTTTCAGGAAATCGGAGAAGATATGGCTGCTGCTTTGCAAGGCGGTCAAGGCTATGCGGACAAGGTGGCGAGCTA
TCCTTTCTTTAAGAAAGAATTGTCCCTGATGATCGAGTATGGTGAGGTCAAATCCAAGCTAGATAGTGAGCTGGAAGTCT
ATGCTGAAAAGACTTGGGAGGAATTTTTCCTACGTATCAACCGAGCCATGAATTTCATTCAGCCCCTAGTATTTATTTTT
GTTGCCTTAGTGATTGTTTTACTTTATGCGGCAATGCTCTTGCCCATTTATCAGAATATGGAGGTTCATTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.547

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

69.94

97.674

0.683
  comGB/cglB Streptococcus mitis SK321

68.75

97.674

0.672
  comGB/cglB Streptococcus pneumoniae TIGR4

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae R6

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae Rx1

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae D39

68.155

97.674

0.666
  comYB Streptococcus mutans UA140

60.641

99.709

0.605
  comYB Streptococcus mutans UA159

60.641

99.709

0.605
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.965

0.494

Multiple sequence alignment