Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQM55_RS10780 Genome accession   NZ_LS483364
Coordinates   2163038..2163979 (-) Length   313 a.a.
NCBI ID   WP_111676749.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11086     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2158038..2168979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS10745 (NCTC11086_02176) comYH 2159263..2160228 (-) 966 WP_111676739.1 class I SAM-dependent methyltransferase Machinery gene
  DQM55_RS10750 (NCTC11086_02177) comGG 2160310..2160702 (-) 393 WP_002907445.1 competence type IV pilus minor pilin ComGG -
  DQM55_RS10755 (NCTC11086_02178) comGF/cglF 2160683..2161120 (-) 438 WP_111676741.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM55_RS10760 (NCTC11086_02179) comGE/cglE 2161104..2161397 (-) 294 WP_111676743.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM55_RS10765 (NCTC11086_02180) comYD 2161363..2161797 (-) 435 WP_172454771.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM55_RS10770 (NCTC11086_02181) comYC 2161757..2162074 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM55_RS10775 (NCTC11086_02182) comYB 2162074..2163108 (-) 1035 WP_269459928.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM55_RS10780 (NCTC11086_02183) comYA 2163038..2163979 (-) 942 WP_111676749.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM55_RS10785 (NCTC11086_02184) - 2164109..2164489 (-) 381 WP_002903497.1 DUF1033 family protein -
  DQM55_RS10795 (NCTC11086_02185) - 2164866..2165972 (-) 1107 WP_172454772.1 glycosyl hydrolase family 8 -
  DQM55_RS10800 (NCTC11086_02186) - 2165981..2167291 (-) 1311 WP_002896777.1 glycosyltransferase family 2 protein -
  DQM55_RS10805 (NCTC11086_02187) - 2167284..2167427 (-) 144 WP_002896778.1 hypothetical protein -
  DQM55_RS10810 (NCTC11086_02188) - 2167439..2168227 (-) 789 WP_002896779.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35869.11 Da        Isoelectric Point: 6.1764

>NTDB_id=1138697 DQM55_RS10780 WP_111676749.1 2163038..2163979(-) (comYA) [Streptococcus sanguinis strain NCTC11086]
MVQEIAKEMIRQARQEGAQDIYLIPKTTCYELYMRIGDERRFIKTYDFELLSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CGEAKVSIRLSSVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSDQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHEAAVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1138697 DQM55_RS10780 WP_111676749.1 2163038..2163979(-) (comYA) [Streptococcus sanguinis strain NCTC11086]
ATGGTTCAAGAAATTGCAAAAGAAATGATTAGGCAGGCTCGGCAAGAAGGGGCGCAGGATATTTACCTCATTCCTAAGAC
TACTTGCTATGAGCTTTATATGAGAATCGGTGATGAACGTCGCTTTATTAAGACTTATGATTTTGAACTTCTGTCAGCTG
TTATCAGCCACTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGCAGTCAGCTGGGGTCTTGCGATTATGAC
TGTGGGGAAGCCAAGGTTTCAATTCGGCTGTCGTCAGTTGGGGATTACCGTGGTTTTGAAAGTCTGGTTATCCGGCTCCT
TCATGACGAAGACAGGGAGCTGCGCTTTTGGTTTGAGCAATTGCCGGAGCTGCGAAAGAAAATTCAGGCTCGCGGTCTCT
ATCTTTTCTCAGGACCAGTCGGCAGTGGCAAGACGACCTTGATGTACCATTTGGCTCAGCTTAAATTTTCTGATCAGCAG
GTTATGTCGATTGAAGATCCGGTTGAGATTAAGCAAGAGGCTATGCTGCAGCTGCAACTGAACGAAACCATTGGCATGAC
TTATGACAGTCTGATTAAGCTGTCTCTGCGACATCGTCCGGATCTCTTGATTATCGGGGAAATCCGTGATCGAGAGACAG
CTAGGGCAGTGGTTCGGGCAAGTTTGACCGGAGCTACGGTCTTTTCAACGATTCATGCCAAGAGTGTTCGCGGTGTCTAT
GAGCGACTTTTGGAATTGGGCGTTAGCGAGGATGAGCTAAGAATGGTGCTTCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGAGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACGAAGCCGCAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80

99.042

0.792
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae D39

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae R6

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

74.441

100

0.744
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.121

100

0.741
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

99.042

0.642
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

40.647

88.818

0.361

Multiple sequence alignment