Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   E0F32_RS09755 Genome accession   NZ_LR216050
Coordinates   1798313..1798792 (-) Length   159 a.a.
NCBI ID   WP_000588925.1    Uniprot ID   A0AAX3HEV8
Organism   Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1793313..1803792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F32_RS09755 (SAMEA3431333_01833) comX/comX2 1798313..1798792 (-) 480 WP_000588925.1 sigma-70 family RNA polymerase sigma factor Regulator
  E0F32_RS09760 (SAMEA3431333_01834) nusG 1799020..1799556 (-) 537 WP_000376736.1 transcription termination/antitermination protein NusG -
  E0F32_RS09765 (SAMEA3431333_01835) secE 1799611..1799787 (-) 177 WP_001210991.1 preprotein translocase subunit SecE -
  E0F32_RS09770 rpmG 1799797..1799949 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  E0F32_RS09775 (SAMEA3431333_01836) pbp2a 1800002..1802197 (-) 2196 WP_000762624.1 penicillin-binding protein PBP2A -
  E0F32_RS09780 (SAMEA3431333_01837) - 1802284..1803159 (+) 876 WP_001861296.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19887.54 Da        Isoelectric Point: 7.3798

>NTDB_id=1126140 E0F32_RS09755 WP_000588925.1 1798313..1798792(-) (comX/comX2) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=1126140 E0F32_RS09755 WP_000588925.1 1798313..1798792(-) (comX/comX2) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGAGCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAGACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAACAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae TIGR4

100

100

1
  comX/comX1 Streptococcus pneumoniae TIGR4

100

100

1
  comX/comX2 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

89.937

100

0.899
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

88.608

99.371

0.881
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus suis D9

46.358

94.969

0.44
  comX/sigX Streptococcus suis isolate S10

46.358

94.969

0.44
  comX/sigX Streptococcus suis P1/7

46.358

94.969

0.44
  comX/sigX Streptococcus mutans UA159

46

94.34

0.434
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX Streptococcus salivarius SK126

38.926

93.711

0.365
  comX Streptococcus thermophilus LMG 18311

38.926

93.711

0.365
  comX Streptococcus thermophilus LMD-9

38.926

93.711

0.365

Multiple sequence alignment