Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   A66_RS09240 Genome accession   NZ_LN847353
Coordinates   1756273..1756599 (-) Length   108 a.a.
NCBI ID   WP_000738630.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain A66     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1751273..1761599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS09205 (A66_01837) comYH 1751679..1752632 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  A66_RS09210 - 1752911..1753514 (+) 604 Protein_1790 transposase family protein -
  A66_RS09215 (A66_01840) - 1753665..1754141 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  A66_RS09220 (A66_01841) comGG/cglG 1754796..1755209 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  A66_RS09225 (A66_01842) comGF/cglF 1755187..1755648 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  A66_RS09230 (A66_01843) comGE/cglE 1755611..1755913 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  A66_RS09235 (A66_01844) comGD/cglD 1755876..1756280 (-) 405 WP_050365326.1 competence type IV pilus minor pilin ComGD Machinery gene
  A66_RS09240 (A66_01845) comGC/cglC 1756273..1756599 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  A66_RS09245 (A66_01846) comGB/cglB 1756601..1757617 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  A66_RS09250 (A66_01847) comGA/cglA/cilD 1757565..1758506 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  A66_RS09255 (A66_01848) - 1758582..1758947 (-) 366 WP_000286415.1 DUF1033 family protein -
  A66_RS09260 (A66_01849) - 1759098..1760156 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  A66_RS09265 (A66_01850) nagA 1760319..1761470 (-) 1152 WP_001134454.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12247.38 Da        Isoelectric Point: 9.8692

>NTDB_id=1114603 A66_RS09240 WP_000738630.1 1756273..1756599(-) (comGC/cglC) [Streptococcus pneumoniae strain A66]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1114603 A66_RS09240 WP_000738630.1 1756273..1756599(-) (comGC/cglC) [Streptococcus pneumoniae strain A66]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954

  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926

  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861

  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648

  comYC Streptococcus mutans UA159

62.745

94.444

0.593

  comYC Streptococcus mutans UA140

62.745

94.444

0.593

  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519

  comYC Streptococcus suis isolate S10

67.901

75

0.509

  comGC Staphylococcus aureus MW2

46.078

94.444

0.435

  comGC Staphylococcus aureus N315

46.078

94.444

0.435

  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361


Multiple sequence alignment