Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   A66_RS09205 Genome accession   NZ_LN847353
Coordinates   1751679..1752632 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain A66     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1746679..1757632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS09180 (A66_01831) - 1747440..1748063 (-) 624 WP_000932660.1 hypothetical protein -
  A66_RS09185 (A66_01832) jag 1748114..1749100 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  A66_RS09190 (A66_01833) - 1749119..1749943 (-) 825 WP_201417385.1 membrane protein insertase YidC -
  A66_RS09195 (A66_01834) rnpA 1749918..1750289 (-) 372 WP_000739244.1 ribonuclease P protein component -
  A66_RS12810 (A66_01835) - 1750306..1750437 (-) 132 WP_000768904.1 hypothetical protein -
  A66_RS09200 (A66_01836) - 1750438..1751628 (-) 1191 WP_053039772.1 acetate kinase -
  A66_RS09205 (A66_01837) comYH 1751679..1752632 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  A66_RS09210 - 1752911..1753514 (+) 604 Protein_1790 transposase family protein -
  A66_RS09215 (A66_01840) - 1753665..1754141 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  A66_RS09220 (A66_01841) comGG/cglG 1754796..1755209 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  A66_RS09225 (A66_01842) comGF/cglF 1755187..1755648 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  A66_RS09230 (A66_01843) comGE/cglE 1755611..1755913 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  A66_RS09235 (A66_01844) comGD/cglD 1755876..1756280 (-) 405 WP_050365326.1 competence type IV pilus minor pilin ComGD Machinery gene
  A66_RS09240 (A66_01845) comGC/cglC 1756273..1756599 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  A66_RS09245 (A66_01846) comGB/cglB 1756601..1757617 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=1114598 A66_RS09205 WP_000345126.1 1751679..1752632(-) (comYH) [Streptococcus pneumoniae strain A66]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1114598 A66_RS09205 WP_000345126.1 1751679..1752632(-) (comYH) [Streptococcus pneumoniae strain A66]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment