Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA2   Type   Machinery gene
Locus tag   LFA_RS09670 Genome accession   NZ_LN614827
Coordinates   2401145..2401558 (-) Length   137 a.a.
NCBI ID   WP_045096006.1    Uniprot ID   A0A098G4W1
Organism   Legionella fallonii LLAP-10     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2396145..2406558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LFA_RS09645 (LFA_2135) - 2396276..2397742 (-) 1467 WP_045096001.1 hypothetical protein -
  LFA_RS09650 (LFA_2136) pilA2 2397893..2398297 (-) 405 WP_045096002.1 pilin Machinery gene
  LFA_RS09655 (LFA_2137) pilA2 2398422..2398835 (-) 414 WP_045096003.1 pilin Machinery gene
  LFA_RS09660 (LFA_2138) - 2399158..2399481 (+) 324 WP_045096004.1 BolA family transcriptional regulator -
  LFA_RS09665 (LFA_2139) - 2399677..2401077 (+) 1401 WP_045096005.1 APC family permease -
  LFA_RS09670 (LFA_2140) pilA2 2401145..2401558 (-) 414 WP_045096006.1 pilin Machinery gene
  LFA_RS09675 (LFA_2141) kdsB 2401790..2402533 (-) 744 WP_045096007.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  LFA_RS09680 (LFA_2142) - 2402530..2402709 (-) 180 WP_045096008.1 Trm112 family protein -
  LFA_RS09685 (LFA_2143) tsaB 2402702..2403376 (-) 675 WP_231865931.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB -
  LFA_RS09690 (LFA_2144) - 2403354..2405312 (-) 1959 WP_045096010.1 ATP-dependent DNA helicase -
  LFA_RS09695 (LFA_2145) fdxA 2405300..2405635 (-) 336 WP_045096011.1 ferredoxin FdxA -

Sequence

Protein


Download         Length: 137 a.a.        Molecular weight: 14153.32 Da        Isoelectric Point: 6.1608

>NTDB_id=1113624 LFA_RS09670 WP_045096006.1 2401145..2401558(-) (pilA2) [Legionella fallonii LLAP-10]
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVTEGLQMASSAQLAVSETTMTNNALPATQTATGYTTPAATPNV
ASIAVSNDGLAVITITYTATAGGGTITLTPTLTTNGDVTWVCKVGTELPKYAPASCR

Nucleotide


Download         Length: 414 bp        

>NTDB_id=1113624 LFA_RS09670 WP_045096006.1 2401145..2401558(-) (pilA2) [Legionella fallonii LLAP-10]
ATGAGACAAAAGGGTTTTACGTTAATTGAATTAATGATAGTTGTGGCAATTATTGGTATTTTAGCCGCTATTGCTATTCC
AGCTTATCAAGACTACACGATTAGAGCGCGCGTGACAGAAGGGCTGCAAATGGCTTCATCAGCCCAATTAGCCGTTTCAG
AAACGACTATGACGAATAATGCCTTACCTGCTACGCAAACAGCAACAGGCTATACTACTCCCGCAGCGACCCCCAACGTT
GCCTCAATTGCAGTATCAAATGATGGTCTTGCTGTAATCACTATCACTTATACAGCCACGGCTGGTGGTGGGACAATTAC
CCTAACCCCCACCCTTACTACTAACGGAGATGTGACTTGGGTCTGTAAGGTTGGAACAGAGTTACCTAAATATGCTCCGG
CTAGCTGCAGATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(2-25)

Pilin (bacterial filament) (Pilin)

(35-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098G4W1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA2 Legionella pneumophila str. Paris

81.022

100

0.81
  pilA2 Legionella pneumophila strain ERS1305867

80.292

100

0.803
  pilA Ralstonia pseudosolanacearum GMI1000

45.963

100

0.54
  comP Acinetobacter baylyi ADP1

50.685

100

0.54
  pilE Neisseria elongata subsp. glycolytica ATCC 29315

36.957

100

0.496
  pilA Pseudomonas aeruginosa PAK

40.94

100

0.445
  pilA/pilA1 Eikenella corrodens VA1

39.073

100

0.431
  pilE Neisseria gonorrhoeae MS11

37.107

100

0.431
  pilA/pilAI Pseudomonas stutzeri DSM 10701

41.429

100

0.423
  pilA Acinetobacter baumannii strain A118

43.284

97.81

0.423
  pilA Vibrio cholerae C6706

36.735

100

0.394
  pilA Vibrio cholerae O1 biovar El Tor strain E7946

36.735

100

0.394
  pilA Vibrio cholerae strain A1552

36.735

100

0.394
  comF Acinetobacter baylyi ADP1

39.098

97.08

0.38

Multiple sequence alignment