Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilA2   Type   Machinery gene
Locus tag   LFA_RS09650 Genome accession   NZ_LN614827
Coordinates   2397893..2398297 (-) Length   134 a.a.
NCBI ID   WP_045096002.1    Uniprot ID   A0A098G6C6
Organism   Legionella fallonii LLAP-10     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2392893..2403297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LFA_RS09635 (LFA_2133) - 2394540..2395724 (+) 1185 WP_052673930.1 LegC2/C7 family Dot/Icm T4SS effector -
  LFA_RS09640 (LFA_2134) - 2396020..2396205 (-) 186 WP_045096000.1 hypothetical protein -
  LFA_RS09645 (LFA_2135) - 2396276..2397742 (-) 1467 WP_045096001.1 hypothetical protein -
  LFA_RS09650 (LFA_2136) pilA2 2397893..2398297 (-) 405 WP_045096002.1 pilin Machinery gene
  LFA_RS09655 (LFA_2137) pilA2 2398422..2398835 (-) 414 WP_045096003.1 pilin Machinery gene
  LFA_RS09660 (LFA_2138) - 2399158..2399481 (+) 324 WP_045096004.1 BolA family transcriptional regulator -
  LFA_RS09665 (LFA_2139) - 2399677..2401077 (+) 1401 WP_045096005.1 APC family permease -
  LFA_RS09670 (LFA_2140) pilA2 2401145..2401558 (-) 414 WP_045096006.1 pilin Machinery gene
  LFA_RS09675 (LFA_2141) kdsB 2401790..2402533 (-) 744 WP_045096007.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  LFA_RS09680 (LFA_2142) - 2402530..2402709 (-) 180 WP_045096008.1 Trm112 family protein -

Sequence


Protein


Download         Length: 134 a.a.        Molecular weight: 14219.37 Da        Isoelectric Point: 4.7738

>NTDB_id=1113622 LFA_RS09650 WP_045096002.1 2397893..2398297(-) (pilA2) [Legionella fallonii LLAP-10]
MYDRGFTLIEILITITIIGILIAIAIPAYQNYTIRVRVSDGLDLASGAQLAVNEYTMINNQLPATAADTQYTSPAATPNV
SSIVMGNLGVITVNYTASAGNGSIILVPTLQVGGLTWDCTRGTLPAQYRPPSCR

Nucleotide


Download         Length: 405 bp        

>NTDB_id=1113622 LFA_RS09650 WP_045096002.1 2397893..2398297(-) (pilA2) [Legionella fallonii LLAP-10]
ATGTATGACAGAGGTTTTACCTTAATCGAAATTTTGATCACTATTACTATCATAGGAATTCTGATTGCAATCGCAATACC
CGCATACCAGAATTATACCATCAGGGTTCGTGTCAGTGACGGTCTGGATTTAGCATCAGGGGCGCAGTTGGCGGTTAATG
AATATACTATGATCAATAATCAACTCCCAGCAACTGCTGCTGATACTCAATATACCTCTCCTGCCGCAACGCCTAATGTT
TCTTCTATTGTAATGGGGAATTTGGGTGTTATTACTGTCAATTATACTGCTAGTGCGGGTAACGGCTCTATTATTCTAGT
TCCTACTTTGCAAGTAGGGGGCTTAACTTGGGATTGTACTAGAGGAACTTTACCTGCACAGTATCGTCCACCATCTTGCC
GATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A098G6C6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA2 Legionella pneumophila strain ERS1305867

64.444

100

0.649

  pilA2 Legionella pneumophila str. Paris

63.704

100

0.642

  pilA Ralstonia pseudosolanacearum GMI1000

37.888

100

0.455

  comP Acinetobacter baylyi ADP1

40

100

0.433

  pilE Neisseria elongata subsp. glycolytica ATCC 29315

30.601

100

0.418

  pilA/pilAII Pseudomonas stutzeri DSM 10701

36.242

100

0.403

  pilA Haemophilus influenzae 86-028NP

37.41

100

0.388

  pilA Haemophilus influenzae Rd KW20

35.971

100

0.373


Multiple sequence alignment