Detailed information NTG1070778

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: ACIVIR_RS00840
• Genome accession: NZ_CP173225
• Coordinates: 134922..135248 (-)
• Length: 108 a.a.
• NCBI ID: WP_000738632.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 262
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 129922..140248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIVIR_RS00795	rnpA	129939..130310 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ACIVIR_RS00800	-	130327..130458 (-)	132	WP_000768904.1	hypothetical protein	-
ACIVIR_RS00805	-	130459..131649 (-)	1191	WP_000167766.1	acetate kinase	-
ACIVIR_RS00810	comYH	131700..132653 (-)	954	WP_050308921.1	class I SAM-dependent methyltransferase	Machinery gene
ACIVIR_RS00815	-	132714..133308 (-)	595	Protein_133	class I SAM-dependent methyltransferase	-
ACIVIR_RS00820	comGG/cglG	133445..133858 (-)	414	WP_050102600.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACIVIR_RS00825	comGF/cglF	133836..134297 (-)	462	WP_000250544.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACIVIR_RS00830	comGE/cglE	134260..134562 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACIVIR_RS00835	comGD/cglD	134525..134929 (-)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACIVIR_RS00840	comGC/cglC	134922..135248 (-)	327	WP_000738632.1	comG operon protein ComGC	Machinery gene
ACIVIR_RS00845	comGB/cglB	135250..136266 (-)	1017	WP_114880773.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACIVIR_RS00850	comGA/cglA/cilD	136214..137155 (-)	942	WP_000249549.1	competence type IV pilus ATPase ComGA	Machinery gene
ACIVIR_RS00855	-	137231..137596 (-)	366	WP_000286415.1	DUF1033 family protein	-
ACIVIR_RS00860	-	137747..138805 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
ACIVIR_RS00865	nagA	138968..140119 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12180.34 Da
• Isoelectric Point: 10.0305

>NTDB_id=1070778 ACIVIR_RS00840 WP_000738632.1 134922..135248(-) (comGC/cglC) [Streptococcus pneumoniae strain 262]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQVKAYKEYNDKNGGANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=1070778 ACIVIR_RS00840 WP_000738632.1 134922..135248(-) (comGC/cglC) [Streptococcus pneumoniae strain 262]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGTTAAAGCTTATAAAGAATACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comGC/cglC	Streptococcus pneumoniae Rx1	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae D39	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae R6	95.37	100	0.954
comGC/cglC	Streptococcus mitis SK321	92.593	100	0.926
comGC/cglC	Streptococcus mitis NCTC 12261	91.919	91.667	0.843
comYC	Streptococcus gordonii str. Challis substr. CH1	66.99	95.37	0.639
comYC	Streptococcus mutans UA159	61.765	94.444	0.583
comYC	Streptococcus mutans UA140	61.765	94.444	0.583
comGC	Lactococcus lactis subsp. cremoris KW2	55.882	94.444	0.528
comYC	Streptococcus suis isolate S10	66.667	75	0.5
comGC	Staphylococcus aureus MW2	48.837	79.63	0.389
comGC	Staphylococcus aureus N315	48.837	79.63	0.389
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361