Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ACIVIR_RS00830 Genome accession   NZ_CP173225
Coordinates   134260..134562 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 262     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 129260..139562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIVIR_RS00795 rnpA 129939..130310 (-) 372 WP_000739246.1 ribonuclease P protein component -
  ACIVIR_RS00800 - 130327..130458 (-) 132 WP_000768904.1 hypothetical protein -
  ACIVIR_RS00805 - 130459..131649 (-) 1191 WP_000167766.1 acetate kinase -
  ACIVIR_RS00810 comYH 131700..132653 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  ACIVIR_RS00815 - 132714..133308 (-) 595 Protein_133 class I SAM-dependent methyltransferase -
  ACIVIR_RS00820 comGG/cglG 133445..133858 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACIVIR_RS00825 comGF/cglF 133836..134297 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACIVIR_RS00830 comGE/cglE 134260..134562 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACIVIR_RS00835 comGD/cglD 134525..134929 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACIVIR_RS00840 comGC/cglC 134922..135248 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  ACIVIR_RS00845 comGB/cglB 135250..136266 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACIVIR_RS00850 comGA/cglA/cilD 136214..137155 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  ACIVIR_RS00855 - 137231..137596 (-) 366 WP_000286415.1 DUF1033 family protein -
  ACIVIR_RS00860 - 137747..138805 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=1070776 ACIVIR_RS00830 WP_000413380.1 134260..134562(-) (comGE/cglE) [Streptococcus pneumoniae strain 262]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1070776 ACIVIR_RS00830 WP_000413380.1 134260..134562(-) (comGE/cglE) [Streptococcus pneumoniae strain 262]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment