Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
| Location | 414600..415215 | Replicon | chromosome |
| Accession | NZ_OW443148 | ||
| Organism | Vibrio cholerae strain CNRVC190243 isolate YE-NCPHL-19014-PI | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | Q9KMG5 |
| Locus tag | OC617_RS15975 | Protein ID | WP_001162670.1 |
| Coordinates | 414600..414887 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | OC617_RS15980 | Protein ID | WP_001232701.1 |
| Coordinates | 414898..415215 (+) | Length | 106 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OC617_RS15915 | 409943..410118 | + | 176 | Protein_405 | acetyltransferase | - |
| OC617_RS15920 | 410179..410331 | + | 153 | Protein_406 | DUF645 family protein | - |
| OC617_RS15925 (CNRVC190243H_03139) | 410525..410842 | - | 318 | WP_001180243.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| OC617_RS15930 (CNRVC190243H_03140) | 410861..411103 | - | 243 | WP_000557292.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| OC617_RS15935 (CNRVC190243H_03141) | 411345..411854 | + | 510 | WP_000405987.1 | GNAT family N-acetyltransferase | - |
| OC617_RS15940 (CNRVC190243H_03142) | 411911..412564 | + | 654 | WP_000226874.1 | hypothetical protein | - |
| OC617_RS15945 | 412653..412862 | + | 210 | WP_001900246.1 | DUF3709 domain-containing protein | - |
| OC617_RS15950 | 412874..413092 | + | 219 | WP_001917086.1 | DUF3709 domain-containing protein | - |
| OC617_RS15955 | 413281..413474 | + | 194 | Protein_413 | hypothetical protein | - |
| OC617_RS15960 | 413495..413728 | + | 234 | WP_032482776.1 | DUF3709 domain-containing protein | - |
| OC617_RS15965 | 414153..414333 | + | 181 | Protein_415 | DUF645 family protein | - |
| OC617_RS15970 | 414446..414559 | + | 114 | WP_001894955.1 | hypothetical protein | - |
| OC617_RS15975 (CNRVC190243H_03143) | 414600..414887 | + | 288 | WP_001162670.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| OC617_RS15980 (CNRVC190243H_03144) | 414898..415215 | + | 318 | WP_001232701.1 | HigA family addiction module antitoxin | Antitoxin |
| OC617_RS15985 | 415212..415322 | + | 111 | WP_134814058.1 | DUF3265 domain-containing protein | - |
| OC617_RS15990 | 415361..415471 | + | 111 | Protein_420 | acetyltransferase | - |
| OC617_RS15995 | 415499..415624 | + | 126 | WP_001944767.1 | DUF645 family protein | - |
| OC617_RS16000 | 415587..415703 | + | 117 | WP_001889170.1 | hypothetical protein | - |
| OC617_RS16005 (CNRVC190243H_03145) | 415891..416895 | + | 1005 | WP_000964925.1 | LD-carboxypeptidase | - |
| OC617_RS16010 (CNRVC190243H_03146) | 417048..417494 | + | 447 | WP_000128977.1 | hypothetical protein | - |
| OC617_RS16015 (CNRVC190243H_03147) | 417614..418543 | + | 930 | WP_000335802.1 | hypothetical protein | - |
| OC617_RS16020 | 418540..418650 | + | 111 | WP_071917832.1 | DUF3265 domain-containing protein | - |
| OC617_RS16025 (CNRVC190243H_03148) | 418678..419154 | + | 477 | WP_001047180.1 | GNAT family N-acetyltransferase | - |
| OC617_RS16030 (CNRVC190243H_03149) | 419345..419806 | + | 462 | WP_001911752.1 | lipocalin family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | catB9 | - | 349905..456410 | 106505 | |
| inside | Integron | catB9 | - | 354985..456034 | 101049 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|