Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
| Location | 778547..779162 | Replicon | chromosome |
| Accession | NZ_CP102928 | ||
| Organism | Vibrio cholerae strain N1252 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | Q9KMG5 |
| Locus tag | NW313_RS17595 | Protein ID | WP_001162670.1 |
| Coordinates | 778547..778834 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | NW313_RS17600 | Protein ID | WP_001232701.1 |
| Coordinates | 778845..779162 (+) | Length | 106 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NW313_RS17535 | 773890..774065 | + | 176 | Protein_730 | acetyltransferase | - |
| NW313_RS17540 | 774126..774278 | + | 153 | Protein_731 | DUF645 family protein | - |
| NW313_RS17545 | 774472..774789 | - | 318 | WP_001180243.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NW313_RS17550 | 774808..775050 | - | 243 | WP_000557292.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| NW313_RS17555 | 775292..775801 | + | 510 | WP_000405987.1 | GNAT family N-acetyltransferase | - |
| NW313_RS17560 | 775858..776511 | + | 654 | WP_000226874.1 | hypothetical protein | - |
| NW313_RS17565 | 776600..776809 | + | 210 | WP_001900246.1 | DUF3709 domain-containing protein | - |
| NW313_RS17570 | 776821..777039 | + | 219 | WP_001917086.1 | DUF3709 domain-containing protein | - |
| NW313_RS17575 | 777228..777421 | + | 194 | Protein_738 | hypothetical protein | - |
| NW313_RS17580 | 777442..777675 | + | 234 | WP_032482776.1 | DUF3709 domain-containing protein | - |
| NW313_RS17585 | 778100..778280 | + | 181 | Protein_740 | DUF645 family protein | - |
| NW313_RS17590 | 778393..778506 | + | 114 | WP_001894955.1 | hypothetical protein | - |
| NW313_RS17595 | 778547..778834 | + | 288 | WP_001162670.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| NW313_RS17600 | 778845..779162 | + | 318 | WP_001232701.1 | HigA family addiction module antitoxin | Antitoxin |
| NW313_RS17605 | 779159..779269 | + | 111 | WP_134814058.1 | DUF3265 domain-containing protein | - |
| NW313_RS17610 | 779308..779418 | + | 111 | Protein_745 | acetyltransferase | - |
| NW313_RS17615 | 779446..779571 | + | 126 | WP_001944767.1 | DUF645 family protein | - |
| NW313_RS17620 | 779534..779650 | + | 117 | WP_001889170.1 | hypothetical protein | - |
| NW313_RS17625 | 779838..780842 | + | 1005 | WP_000964925.1 | LD-carboxypeptidase | - |
| NW313_RS17630 | 780995..781441 | + | 447 | WP_000128977.1 | hypothetical protein | - |
| NW313_RS17635 | 781561..782490 | + | 930 | WP_000335802.1 | hypothetical protein | - |
| NW313_RS17640 | 782487..782597 | + | 111 | WP_071917832.1 | DUF3265 domain-containing protein | - |
| NW313_RS17645 | 782625..783101 | + | 477 | WP_001047171.1 | GNAT family N-acetyltransferase | - |
| NW313_RS17650 | 783292..783753 | + | 462 | WP_001911752.1 | lipocalin family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | catB9 | - | 713852..820357 | 106505 | |
| inside | Integron | catB9 | - | 718932..819981 | 101049 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|