Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) dhiT-phd/-
Location 972984..973388 Replicon chromosome
Accession NZ_CP040173
Organism Vibrio cholerae strain VC1374

Toxin (Protein)


Gene name dhiT Uniprot ID A0A086SLD6
Locus tag FDZ90_RS19335 Protein ID WP_001114075.1
Coordinates 973119..973388 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag FDZ90_RS19330 Protein ID WP_099607150.1
Coordinates 972984..973088 (+) Length 35 a.a.

Genomic Context

FDZ90_RS19295FDZ90_RS19300FDZ90_RS19305FDZ90_RS19310FDZ90_RS19315FDZ90_RS19320FDZ90_RS19325FDZ90_RS19330FDZ90_RS19335FDZ90_RS19340FDZ90_RS19345FDZ90_RS19350FDZ90_RS19365FDZ90_RS19370FDZ90_RS19355FDZ90_RS19360
Location: 968486..969403 (918 bp)
Type: Others
Protein ID: WP_000186333.1
Location: 969560..969949 (390 bp)
Type: Others
Protein ID: WP_001081302.1
Location: 970085..970294 (210 bp)
Type: Others
Protein ID: Protein_914
Location: 970413..970850 (438 bp)
Type: Others
Protein ID: WP_000503169.1
Location: 970913..971131 (219 bp)
Type: Others
Protein ID: WP_071908318.1
Location: 971306..972178 (873 bp)
Type: Others
Protein ID: WP_000254716.1
Location: 972328..972927 (600 bp)
Type: Others
Protein ID: WP_001891245.1
Location: 972984..973088 (105 bp)
Type: Antitoxin
Protein ID: WP_099607150.1
Location: 973119..973388 (270 bp)
Type: Toxin
Protein ID: WP_001114075.1
Location: 973382..973903 (522 bp)
Type: Others
Protein ID: WP_000921691.1
Location: 974202..974327 (126 bp)
Type: Others
Protein ID: WP_001905700.1
Location: 974578..974973 (396 bp)
Type: Others
Protein ID: WP_001000867.1
Location: 975865..976380 (516 bp)
Type: Others
Protein ID: WP_000343779.1
Location: 976564..976977 (414 bp)
Type: Others
Protein ID: WP_000049420.1
Location: 975112..975390 (279 bp)
Type: Others
Protein ID: WP_000578476.1
Location: 975387..975671 (285 bp)
Type: Others
Protein ID: WP_000381183.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FDZ90_RS19295968486..969403+918WP_000186333.1alpha/beta hydrolase-
FDZ90_RS19300969560..969949+390WP_001081302.1hypothetical protein-
FDZ90_RS19305970085..970294+210Protein_914GNAT family N-acetyltransferase-
FDZ90_RS19310970413..970850+438WP_000503169.1IS200/IS605-like element IS1004 family transposase-
FDZ90_RS19315970913..971131+219WP_071908318.1GNAT family N-acetyltransferase-
FDZ90_RS19320971306..972178+873WP_000254716.1DUF3800 domain-containing protein-
FDZ90_RS19325972328..972927+600WP_001891245.1glutathione S-transferase N-terminal domain-containing protein-
FDZ90_RS19330972984..973088+105WP_099607150.1acetyltransferaseAntitoxin
FDZ90_RS19335973119..973388+270WP_001114075.1DUF4160 domain-containing proteinToxin
FDZ90_RS19340973382..973903+522WP_000921691.1DUF2442 domain-containing protein-
FDZ90_RS19345974202..974327+126WP_001905700.1DUF645 family protein-
FDZ90_RS19350974578..974973+396WP_001000867.1hypothetical protein-
FDZ90_RS19355975112..975390-279WP_000578476.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family-
FDZ90_RS19360975387..975671-285WP_000381183.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
FDZ90_RS19365975865..976380+516WP_000343779.1GNAT family N-acetyltransferase-
FDZ90_RS19370976564..976977+414WP_000049420.1VOC family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandcatB9-882589..97784095251
insideIntegroncatB9-887669..97746489795
flankIS/Tn--970413..970850437


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10310.94 Da        Isoelectric Point: 6.6303

>T125050 WP_001114075.1 NZ_CP040173:973119-973388 [Vibrio cholerae]
MPEIDALLGLSFCLYFFDNKQHKLPHIHVKYGSYELIIAIETGECLEGYLPNKQRKRAENHILEHREQLMVMWNKAVNGE
NPGKLGDLC

Download         Length: 270 bp

>T125050 NZ_CP040173:973119-973388 [Vibrio cholerae]
ATGCCAGAGATTGATGCCCTATTAGGTCTTTCATTTTGCTTGTACTTCTTTGATAACAAGCAGCATAAATTACCTCATAT
TCACGTTAAGTACGGTAGTTACGAGCTAATTATTGCTATTGAAACAGGTGAGTGTTTAGAGGGTTACTTACCCAATAAGC
AACGAAAACGTGCTGAAAACCATATTCTTGAACATCGAGAGCAATTGATGGTGATGTGGAATAAAGCGGTGAATGGTGAA
AATCCAGGTAAGTTAGGTGATTTATGTTGA

Antitoxin


Download         Length: 35 a.a.        Molecular weight: 3991.79 Da        Isoelectric Point: 9.2853

>AT125050 WP_099607150.1 NZ_CP040173:972984-973088 [Vibrio cholerae]
VVSVVVFEFSSMRCQPLRRALYAYRNCLLKDTLL

Download         Length: 105 bp

>AT125050 NZ_CP040173:972984-973088 [Vibrio cholerae]
GTGGTTTCGGTTGTTGTGTTTGAGTTTAGTAGTATGCGCTGCCAGCCCCTTAGGCGGGCGTTATATGCTTATAGGAATTG
TCTCCTAAAGGATACGCTGCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A086SLD6

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References