Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00553  |
| T6SS type | Type i3 |
| Strain | Salmonella enterica subsp. enterica serovar Typhimurium str. T000240 |
| Replicon (RefSeq) | chromosome (NC_016860) |
| Location | 304666..332063 |
| Function | - |
| Comment | - |
| References | - |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagJ | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| STMDT12_RS01315 (mltD) | 299924..301291 | - | 1368 | WP_000644706.1 | murein transglycosylase D | ||
| STMDT12_RS01320 (gloB) | 301363..302118 | - | 756 | WP_001052775.1 | hydroxyacylglutathione hydrolase | ||
| STMDT12_RS01325 | 302153..302875 | + | 723 | WP_000801238.1 | class I SAM-dependent methyltransferase | ||
| STMDT12_RS01330 (rnhA) | 302872..303339 | - | 468 | WP_000917872.1 | ribonuclease HI | ||
| STMDT12_RS01335 (dnaQ) | 303403..304134 | + | 732 | WP_001670675.1 | DNA polymerase III subunit epsilon | ||
| T6CP005855 | TssA | STMDT12_RS01345 | 304666..305721 | - | 1056 | WP_000367626.1 | ImpA family type VI secretion system protein |
| T6CP005856 | TssG | STMDT12_RS01350 (tssG) | 305732..306727 | - | 996 | WP_000145244.1 | type VI secretion system baseplate subunit TssG |
| T6CP005857 | TssF | STMDT12_RS01355 (tssF) | 306724..308607 | - | 1884 | WP_000371502.1 | type VI secretion system baseplate subunit TssF |
| T6CP005858 | TssE | STMDT12_RS01360 (tssE) | 308623..309117 | - | 495 | WP_000108007.1 | type VI secretion system baseplate subunit TssE |
| T6CP012827 | TagJ | STMDT12_RS01365 | 309114..309938 | - | 825 | WP_000750535.1 | hypothetical protein |
| STMDT12_RS01370 (tagK) | 309925..310827 | - | 903 | WP_000806681.1 | type VI secretion system-associated protein TagK | ||
| T6CP005859 | TssH | STMDT12_RS01380 (tssH) | 311195..313834 | + | 2640 | WP_000449778.1 | type VI secretion system ATPase TssH |
| T6CP005860 | TssB | STMDT12_RS01385 (tssB) | 313934..314476 | + | 543 | WP_000996817.1 | type VI secretion system contractile sheath small subunit |
| T6CP005861 | TssC | STMDT12_RS01390 (tssC) | 314500..316008 | + | 1509 | WP_000013881.1 | type VI secretion system contractile sheath large subunit |
| STMDT12_RS24960 | 316074..316181 | + | 108 | pseudogene | BPSL0067 family protein | ||
| STMDT12_RS01395 | 316308..316640 | + | 333 | WP_014344502.1 | hypothetical protein | ||
| T6CP005862 | TssD | STMDT12_RS01400 | 316894..317379 | + | 486 | WP_000312802.1 | Hcp family type VI secretion system effector |
| STMDT12_RS27145 | 317399..317554 | + | 156 | WP_001541860.1 | hypothetical protein | ||
| STMDT12_RS01405 | 317684..318169 | + | 486 | WP_001081550.1 | type VI secretion system amidase effector protein Tae4 | ||
| STMDT12_RS01410 | 318154..318537 | + | 384 | WP_000379146.1 | type VI secretion system amidase immunity protein Tai4 | ||
| T6CP005863 | TssD | STMDT12_RS01415 | 318680..319165 | + | 486 | WP_000119443.1 | Hcp family type VI secretion system effector |
| T6CP005864 | TssJ | STMDT12_RS01420 (tssJ) | 319232..319768 | + | 537 | WP_001007106.1 | type VI secretion system lipoprotein TssJ |
| T6CP005865 | TssK | STMDT12_RS01425 (tssK) | 319772..321115 | + | 1344 | WP_000118732.1 | type VI secretion system baseplate subunit TssK |
| T6CP005866 | TssL | STMDT12_RS01430 (tssL) | 321112..322416 | + | 1305 | WP_000132483.1 | type VI secretion system protein TssL, long form |
| STMDT12_RS01435 | 322421..323194 | + | 774 | WP_000976553.1 | membrane protein | ||
| STMDT12_RS01440 | 323397..323828 | + | 432 | WP_000227044.1 | Shiga toxin A subunit | ||
| T6CP005867 | TssM | STMDT12_RS01445 (tssM) | 323862..327731 | + | 3870 | WP_001168955.1 | type VI secretion system membrane subunit TssM |
| STMDT12_RS01450 | 327731..328519 | + | 789 | WP_001254137.1 | DUF2094 domain-containing protein | ||
| STMDT12_RS01455 | 328516..328932 | + | 417 | WP_001596567.1 | DUF2195 family protein | ||
| STMDT12_RS01460 | 328956..329477 | + | 522 | WP_000968384.1 | DUF2778 domain-containing protein | ||
| T6CP005868 | TssI | STMDT12_RS01465 | 329874..332063 | + | 2190 | WP_000011534.1 | type VI secretion system Vgr family protein |
| STMDT12_RS01470 | 332087..332533 | + | 447 | WP_000375832.1 | DcrB-related protein | ||
| T6CP011993 | PAAR | STMDT12_RS01475 | 332552..336646 | + | 4095 | WP_000272656.1 | PAAR domain-containing protein |
| STMDT12_RS01480 | 336640..336903 | + | 264 | WP_000932531.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01380 |
STM0277 (Tae4) | Tae | Salmonella enterica subsp. enterica serovar Typhimurium str. T000240 | chromosome (NC_016860) | 317684..318169 (+) | 378698249 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|