Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00022  |
| T6SS type | Type Unknown |
| Strain | Yersinia pestis CO92 |
| Replicon (RefSeq) | chromosome (NC_003143) |
| Location | 3996574..4033587 |
| Function | - |
| Comment | - |
| References | [1] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | PAAR | TssA | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 2 | 3 | 1 | 1 | 2 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| YPO_RS18875 (lptB) | 3991676..3992401 | + | 726 | WP_002210116.1 | LPS export ABC transporter ATP-binding protein | ||
| YPO_RS18880 (rpoN) | 3992463..3993896 | + | 1434 | WP_002210115.1 | RNA polymerase factor sigma-54 | ||
| YPO_RS18885 (hpf) | 3993920..3994207 | + | 288 | pseudogene | ribosome hibernation promoting factor | ||
| YPO_RS18890 (ptsN) | 3994325..3994807 | + | 483 | WP_002213952.1 | PTS IIA-like nitrogen regulatory protein PtsN | ||
| YPO_RS18895 (rapZ) | 3995113..3995967 | + | 855 | WP_002210113.1 | RNase adapter RapZ | ||
| YPO_RS18900 (npr) | 3995964..3996236 | + | 273 | WP_002210112.1 | PTS phosphocarrier protein NPr | ||
| YPO_RS18905 (pyrB) | 3996574..3997509 | + | 936 | WP_002210111.1 | aspartate carbamoyltransferase | ||
| YPO_RS18910 | 3997521..3997985 | + | 465 | WP_002210110.1 | aspartate carbamoyltransferase regulatory subunit | ||
| YPO_RS18915 (ridA) | 3998123..3998509 | + | 387 | WP_002210109.1 | 2-iminobutanoate/2-iminopropanoate deaminase | ||
| YPO_RS18920 (istA) | 3998850..3999872 | + | 1023 | WP_000255944.1 | IS21-like element IS100 family transposase | ||
| YPO_RS18925 (istB) | 3999872..4000651 | + | 780 | WP_001297096.1 | IS21-like element IS100kyp family helper ATPase IstB | ||
| YPO_RS18930 | 4000718..4000924 | - | 207 | pseudogene | transposase | ||
| YPO_RS18935 | 4000993..4001718 | + | 726 | pseudogene | type VI secretion system baseplate subunit TssF | ||
| T6CP000165 | TssG | YPO_RS18940 (tssG) | 4001682..4002770 | + | 1089 | WP_002213885.1 | type VI secretion system baseplate subunit TssG |
| T6CP011410 | FHA | YPO_RS18945 (tagH) | 4002896..4004212 | + | 1317 | WP_002212103.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP000166 | TssJ | YPO_RS18950 (tssJ) | 4004212..4004757 | + | 546 | WP_002212104.1 | type VI secretion system lipoprotein TssJ |
| T6CP000167 | TssK | YPO_RS18955 (tssK) | 4004760..4006106 | + | 1347 | WP_002212105.1 | type VI secretion system baseplate subunit TssK |
| T6CP000168 | TssL | YPO_RS18960 | 4006106..4006873 | + | 768 | WP_002212106.1 | type IVB secretion system protein IcmH/DotU |
| T6CP000169 | TssH | YPO_RS18965 (tssH) | 4006884..4009487 | + | 2604 | WP_002212107.1 | type VI secretion system ATPase TssH |
| YPO_RS18970 | 4009484..4010281 | + | 798 | WP_002212108.1 | Fis family transcriptional regulator | ||
| YPO_RS18975 (tagO) | 4010278..4010964 | + | 687 | WP_002212109.1 | type VI secretion system-associated protein TagO | ||
| T6CP008415 | TssA | YPO_RS18980 (tssA) | 4010970..4012358 | + | 1389 | WP_002212110.1 | type VI secretion system protein TssA |
| T6CP000170 | TssM | YPO_RS18985 (tssM) | 4012390..4015923 | + | 3534 | WP_002212111.1 | type VI secretion system membrane subunit TssM |
| T6CP008416 | TssA | YPO_RS18990 | 4016048..4016830 | + | 783 | WP_002213880.1 | ImpA family type VI secretion system protein |
| T6CP008417 | TssA | YPO_RS18995 | 4016827..4017360 | + | 534 | WP_002213878.1 | membrane protein |
| T6CP000171 | TssI | YPO_RS19000 | 4017568..4019784 | + | 2217 | WP_029858416.1 | type VI secretion system tip protein VgrG |
| YPO_RS19005 | 4019790..4020248 | + | 459 | WP_002213383.1 | DcrB-related protein | ||
| T6CP011411 | PAAR | YPO_RS19010 | 4020241..4023105 | + | 2865 | WP_002213873.1 | PAAR/RHS domain-containing protein |
| YPO_RS19015 | 4023133..4024503 | + | 1371 | WP_002213871.1 | RHS repeat protein | ||
| YPO_RS19020 | 4024505..4024990 | + | 486 | WP_002213869.1 | SMI1/KNR4 family protein | ||
| YPO_RS19025 | 4025040..4025231 | - | 192 | WP_002213868.1 | SymE family type I addiction module toxin | ||
| YPO_RS19030 | 4025307..4025531 | - | 225 | WP_002213866.1 | type I toxin-antitoxin system SymE family toxin | ||
| YPO_RS19035 | 4025613..4026020 | - | 408 | WP_002210018.1 | helix-turn-helix domain-containing protein | ||
| YPO_RS19040 | 4026114..4026359 | + | 246 | pseudogene | hypothetical protein | ||
| T6CP000172 | TssI | YPO_RS19045 | 4026381..4028579 | + | 2199 | WP_002213863.1 | type VI secretion system tip protein VgrG |
| YPO_RS19050 | 4028582..4029004 | + | 423 | WP_002213861.1 | DcrB-related protein | ||
| T6CP011412 | PAAR | YPO_RS19055 | 4029049..4033587 | + | 4539 | WP_002210022.1 | PAAR/RHS domain-containing protein |
| YPO_RS19060 | 4033596..4034390 | + | 795 | WP_002210023.1 | hypothetical protein | ||
| YPO_RS19065 | 4034448..4034717 | - | 270 | WP_042594322.1 | SymE family type I addiction module toxin | ||
| YPO_RS19070 | 4034737..4035636 | - | 900 | WP_002210024.1 | sugar phosphate isomerase/epimerase | ||
| YPO_RS19075 | 4035633..4036763 | - | 1131 | WP_002210025.1 | Gfo/Idh/MocA family oxidoreductase | ||
| YPO_RS19080 | 4037033..4037899 | + | 867 | WP_002210026.1 | AraC family transcriptional regulator | ||
| YPO_RS19085 (rbsD) | 4038061..4038564 | - | 504 | WP_002210027.1 | D-ribose pyranase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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