SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP000172
Component protein type	TssI
T6SS ID (Type)	T6SS00022 (Type Unknown)
Strain	Yersinia pestis CO92
Replicon	chromosome
Sequence	Protein sequence (733 a.a.); Nucleotide sequence (2199 bp)
Reference	[1] Boyer F, Fichant G, Berthod J, et al. Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? BMC Genomics. 2009 Mar 12;10:104. doi: 10.1186/1471-2164-10-104. PMID: 19284603

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	YPO_RS19045
Coordinate (Strand)	4026381..4028579 (+)
NCBI ID	WP_002213863.1
RefSeq	NC_003143
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
Phage_GPD	PF05954.13	6e-83	134..431
Phage_base_V	PF04717.14	5.8e-14	489..555

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-732	MFAHDKANNNKTADKTGTVTPTHIVSPEAAPTVSGAQMTEMAGGIGDAVGGTAGKRINQAAEVAKTALDAKAKVLDGGVTPLNLAAGGAGAGLPDSAVAALTRLVKQPSGLQFTLTTASLPPQTFAVVDFTLSEMLSSPFVLNVGLASADPAVDFAAVLDEDATLFIWREGVLQRSITGMVASFEQGDTGFHQTRYSMVIRPALWRTSLRRNARIFQQASVEEIITTLLKENGINDFAFGFRHPHPVREFCVQYQESDFDFIQRLTAEEGIFYYFEFSAGKNTVVYADDVGSLPKGASLPYNPNVAAQAQELSITTFTRSAQVRPAMVQLKDYTFKNPNWAAAFSEQSGELQNQRPDYEHFDFPGRFKDAQHGQDFTRYRLDALRNDANLGQGASNDFTLQPGQLFSLYNHPRGDLNHAWQLLGVQHSGKQMQALEQASGDQGTVLFNHFSFIPHTQTWRPTPLAKPAMDGPQIAMVVGPPGEEIYCDEYGRIRLQFLWDRYGQSNDNSSCWIRVTQPWAGQGWGMLAIPRIGQEVVVDFLHGDPDQPIVTGRTYHANNIPPGSLPASKTQMAFRSKTHQGEGYNEMRFEDAKGGEGLFMHAQKDMSTTVKDNQTTTVEKGNQTVTVEKGDRTVTVATGNETTDITQGSLTETIKVRRSTCANFIQVKAEGDAPGTQLYTATEQIKFVVGKSSITLNPDSIILQFSGSTSITLNAANIDAIAPLINLNKDKG

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9507	-	-

Protein sequence: 733 a.a.

						>T6CP000172 NC_003143:4026381-4028579 [Yersinia pestis CO92] [TssI]
MFAHDKANNNKTADKTGTVTPTHIVSPEAAPTVSGAQMTEMAGGIGDAVGGTAGKRINQAAEVAKTALDAKAKVLDGGVT
PLNLAAGGAGAGLPDSAVAALTRLVKQPSGLQFTLTTASLPPQTFAVVDFTLSEMLSSPFVLNVGLASADPAVDFAAVLD
EDATLFIWREGVLQRSITGMVASFEQGDTGFHQTRYSMVIRPALWRTSLRRNARIFQQASVEEIITTLLKENGINDFAFG
FRHPHPVREFCVQYQESDFDFIQRLTAEEGIFYYFEFSAGKNTVVYADDVGSLPKGASLPYNPNVAAQAQELSITTFTRS
AQVRPAMVQLKDYTFKNPNWAAAFSEQSGELQNQRPDYEHFDFPGRFKDAQHGQDFTRYRLDALRNDANLGQGASNDFTL
QPGQLFSLYNHPRGDLNHAWQLLGVQHSGKQMQALEQASGDQGTVLFNHFSFIPHTQTWRPTPLAKPAMDGPQIAMVVGP
PGEEIYCDEYGRIRLQFLWDRYGQSNDNSSCWIRVTQPWAGQGWGMLAIPRIGQEVVVDFLHGDPDQPIVTGRTYHANNI
PPGSLPASKTQMAFRSKTHQGEGYNEMRFEDAKGGEGLFMHAQKDMSTTVKDNQTTTVEKGNQTVTVEKGDRTVTVATGN
ETTDITQGSLTETIKVRRSTCANFIQVKAEGDAPGTQLYTATEQIKFVVGKSSITLNPDSIILQFSGSTSITLNAANIDA
IAPLINLNKDKG*					

Nucleotide sequence: 2199 bp

						>T6CP000172 NC_003143:4026381-4028579 [Yersinia pestis CO92] [TssI]
ATGTTTGCTCATGATAAAGCTAATAATAATAAAACCGCGGACAAGACCGGCACGGTGACGCCGACCCATATCGTCTCGCC
GGAGGCCGCCCCAACCGTGAGTGGCGCTCAGATGACCGAGATGGCCGGGGGGATTGGGGATGCGGTGGGCGGCACTGCCG
GTAAGCGCATTAATCAGGCCGCCGAGGTGGCTAAAACCGCCCTGGATGCCAAAGCAAAAGTCCTGGACGGCGGCGTCACG
CCGCTGAATCTGGCCGCGGGCGGGGCCGGTGCGGGATTACCGGACAGCGCCGTGGCGGCGCTTACCCGCCTGGTCAAACA
GCCCTCCGGCCTGCAATTTACCCTGACGACGGCCAGTTTACCGCCCCAGACCTTTGCGGTGGTGGATTTCACCCTGAGTG
AGATGCTCTCCTCGCCGTTTGTGCTCAATGTCGGGCTGGCGAGTGCCGATCCGGCGGTGGATTTTGCGGCGGTGCTGGAT
GAAGACGCCACGCTGTTTATCTGGCGCGAAGGGGTGCTGCAACGCAGCATCACCGGCATGGTCGCCAGCTTTGAACAGGG
CGATACCGGTTTTCATCAGACCCGCTACAGCATGGTGATCCGCCCGGCGCTGTGGCGCACCAGCCTGCGGCGCAATGCCC
GCATCTTCCAGCAGGCCTCGGTGGAAGAGATCATCACCACCCTGCTGAAAGAGAACGGCATCAACGATTTTGCCTTTGGT
TTTCGCCACCCGCACCCGGTGCGCGAGTTCTGCGTGCAATATCAGGAGTCCGATTTTGATTTTATCCAGCGCCTGACGGC
AGAAGAGGGGATTTTCTACTACTTCGAGTTCAGCGCCGGGAAAAATACCGTGGTGTATGCCGATGATGTCGGCTCCCTGC
CGAAAGGCGCGTCACTGCCCTATAACCCGAATGTGGCGGCGCAGGCGCAGGAACTGAGTATCACCACCTTCACCCGCAGT
GCGCAGGTGCGCCCGGCGATGGTGCAACTGAAGGACTACACCTTTAAAAACCCGAACTGGGCCGCGGCCTTCAGCGAACA
GTCGGGAGAACTGCAAAACCAGCGACCGGACTACGAGCATTTTGATTTTCCGGGGCGCTTCAAAGATGCCCAGCACGGGC
AGGATTTTACCCGCTACCGGCTGGATGCACTGCGCAATGACGCCAATCTGGGGCAGGGGGCGAGCAATGATTTTACCCTC
CAGCCGGGGCAGTTGTTCAGCCTGTACAACCACCCGCGTGGTGATCTGAACCACGCCTGGCAGTTGCTCGGCGTTCAGCA
CAGCGGCAAACAGATGCAGGCGCTGGAGCAGGCGTCTGGCGATCAGGGCACGGTGCTGTTCAACCACTTCAGTTTTATTC
CGCACACCCAGACCTGGCGGCCGACGCCGCTGGCGAAACCGGCGATGGACGGCCCGCAGATCGCCATGGTGGTGGGGCCA
CCGGGGGAAGAGATTTACTGCGACGAATACGGGCGCATCCGCCTGCAATTTTTATGGGATCGCTACGGGCAGAGCAATGA
CAACAGCTCCTGCTGGATCCGGGTAACCCAGCCGTGGGCGGGCCAGGGCTGGGGCATGCTGGCCATTCCGCGTATTGGTC
AGGAAGTGGTGGTGGATTTTCTGCACGGCGATCCGGATCAACCGATTGTCACGGGGCGGACCTATCACGCCAACAACATC
CCGCCGGGGTCGTTACCGGCCAGTAAAACCCAGATGGCGTTCCGCTCAAAAACCCACCAAGGGGAAGGCTACAACGAAAT
GCGCTTCGAGGATGCCAAAGGCGGCGAAGGGCTGTTTATGCATGCGCAGAAAGATATGAGTACCACGGTAAAAGATAACC
AGACGACGACGGTGGAGAAAGGTAATCAAACCGTCACCGTAGAAAAAGGTGACAGGACAGTCACGGTCGCGACCGGAAAT
GAAACCACAGATATTACCCAAGGGAGCCTGACCGAGACGATCAAAGTGCGTCGCAGTACCTGCGCGAATTTTATTCAGGT
GAAGGCTGAAGGTGATGCGCCTGGTACGCAACTTTATACCGCGACGGAACAGATAAAGTTCGTGGTGGGCAAGAGCAGCA
TTACCTTAAATCCGGACTCTATTATTCTGCAATTTTCTGGCTCTACCTCTATTACGCTGAATGCCGCCAATATTGACGCC
ATCGCGCCATTGATTAACTTAAATAAAGACAAGGGATAA					