Detailed information of component protein


Summary

Component ID T6CP000170
Component protein type TssM
T6SS ID (Type) T6SS00022 insolico (Type Unknown)
Strain Yersinia pestis CO92
Replicon chromosome
Sequence Protein sequence (1178 a.a.); Nucleotide sequence (3534 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) YPO_RS18985
Coordinate (Strand) 4012390..4015923 (+)
NCBI ID WP_002212111.1
RefSeq NC_003143
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 1.8e-76 508..821
IcmF-related_N PF14331.8 2.5e-70 203..452
IcmF_C PF06744.14 3.1e-22 1050..1154
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-19 MKLPFFIRIAKPAIPRLKA
Transmembrane helix 20-39 SIPVVLALMACAALIWVWIY
Outside 40-53 GPEWQLGENYPFET
Transmembrane helix 54-76 LLSRWLVTAVFVLVAVCWLSLKV
Inside 77-452 MRRVQHLEKLQLQTKIQLDDPVSADIEQQNHYLNGWKHQLQRHLNTPEYLYRLPWYMVIGARNSGKSTLIKEGYKLTEISASERLHAEDAADLRVRCWLGEQAVIIDPAGVLIEQPTTPIAGKASLNSRLWQSLLSWLIEQRQRQPLNGIILTVDLHQMMTANKAQRETYVADIHQRLQEIRLSLHSQVPLYVVFTKMDLLYGFEAMYQSLDKAEREAVLGVTFSLNAADPDVWRTELKQFWQQWVAQLNGAMPDMMLNSVDAGQRSQLFSFTRQMQGLHDYVVQLLEGILYRGEHAQPLLRGVYLTSAQQRGQMDDIFTQSAAVQYHLAPQAFPTWPVSDTTPYFTKALFNQVLLAEPNLAGENGIWLQKTRKRM
Transmembrane helix 453-470 FIFSGVGALAALTLWGYW
Outside 471-1177 HYYHQLNYRAGEEVLTQAKTFLSIPPPEGDDRYGNLQLPLLNPIRDATLAYGNYHERSPFLADMGLYQGNNIGPYVESTYLQLLQQRFVPALMSGLLEQLNAAPKGSEEKLEILRVMRMLEDGSGRNAALVEQYMSHRWSQQFNGQRELQEQLSSHLNYALKHTDWHGARESGDQYAIKSFVPYLRPIQSAQQELSKLSIYQRVYQNLRIKAQDALPPALDLRDQIGASFDDIFVSGNDRLLVIPQFLTRSGLQSYFIKQNDQLVDLTVMDSWVLNLTKNVEYSEADRKEIHRQVTEQYLGDYTATWRAAMNNLSVSDFEGLPQAISAIEQVISGEQPFRRALQTLSDNTRLPVISDLIPAKEQQELLQKPDYLLLTRINREFSPETAVLVENGDKGSVIQSVYQKLTELHRYLLAIQNSPAPGKAALKAVQLRLDQNNSDPIFEVQQLAKNLPEPLNRWVGELAEQAWRVVMMEAIQSLEVEWNETVIKQYQTYLAGRYPFDPHAKQDVPLSEFERFFGPKGTLDAFYQQNLKPFVENNLTGGSDGELLIRPDVLQQLAQARKIRDTFFSAQNGLGTQFAIEPVLLSGNKRRSVLNLDGQLLDYAHGRSGVVHLVWPNSMRAGVESKLTLVPDESGKSPRTLSFSGPWAQLRLINAGELTNVGTNSFDVRFKVDGGEMTYRIFVDESDNPFAGGLFSKFSLPDTLY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8171 - -


  Protein sequence: 1178 a.a.    

>T6CP000170 NC_003143:4012390-4015923 [Yersinia pestis CO92] [TssM]
MKLPFFIRIAKPAIPRLKASIPVVLALMACAALIWVWIYGPEWQLGENYPFETLLSRWLVTAVFVLVAVCWLSLKVMRRV
QHLEKLQLQTKIQLDDPVSADIEQQNHYLNGWKHQLQRHLNTPEYLYRLPWYMVIGARNSGKSTLIKEGYKLTEISASER
LHAEDAADLRVRCWLGEQAVIIDPAGVLIEQPTTPIAGKASLNSRLWQSLLSWLIEQRQRQPLNGIILTVDLHQMMTANK
AQRETYVADIHQRLQEIRLSLHSQVPLYVVFTKMDLLYGFEAMYQSLDKAEREAVLGVTFSLNAADPDVWRTELKQFWQQ
WVAQLNGAMPDMMLNSVDAGQRSQLFSFTRQMQGLHDYVVQLLEGILYRGEHAQPLLRGVYLTSAQQRGQMDDIFTQSAA
VQYHLAPQAFPTWPVSDTTPYFTKALFNQVLLAEPNLAGENGIWLQKTRKRMFIFSGVGALAALTLWGYWHYYHQLNYRA
GEEVLTQAKTFLSIPPPEGDDRYGNLQLPLLNPIRDATLAYGNYHERSPFLADMGLYQGNNIGPYVESTYLQLLQQRFVP
ALMSGLLEQLNAAPKGSEEKLEILRVMRMLEDGSGRNAALVEQYMSHRWSQQFNGQRELQEQLSSHLNYALKHTDWHGAR
ESGDQYAIKSFVPYLRPIQSAQQELSKLSIYQRVYQNLRIKAQDALPPALDLRDQIGASFDDIFVSGNDRLLVIPQFLTR
SGLQSYFIKQNDQLVDLTVMDSWVLNLTKNVEYSEADRKEIHRQVTEQYLGDYTATWRAAMNNLSVSDFEGLPQAISAIE
QVISGEQPFRRALQTLSDNTRLPVISDLIPAKEQQELLQKPDYLLLTRINREFSPETAVLVENGDKGSVIQSVYQKLTEL
HRYLLAIQNSPAPGKAALKAVQLRLDQNNSDPIFEVQQLAKNLPEPLNRWVGELAEQAWRVVMMEAIQSLEVEWNETVIK
QYQTYLAGRYPFDPHAKQDVPLSEFERFFGPKGTLDAFYQQNLKPFVENNLTGGSDGELLIRPDVLQQLAQARKIRDTFF
SAQNGLGTQFAIEPVLLSGNKRRSVLNLDGQLLDYAHGRSGVVHLVWPNSMRAGVESKLTLVPDESGKSPRTLSFSGPWA
QLRLINAGELTNVGTNSFDVRFKVDGGEMTYRIFVDESDNPFAGGLFSKFSLPDTLY*

  Nucleotide sequence: 3534 bp    

>T6CP000170 NC_003143:4012390-4015923 [Yersinia pestis CO92] [TssM]
ATGAAATTGCCGTTCTTTATACGCATAGCCAAGCCCGCCATTCCTCGCCTTAAAGCGTCAATACCGGTGGTATTGGCGTT
GATGGCTTGTGCGGCACTCATTTGGGTATGGATTTACGGACCCGAGTGGCAATTGGGGGAAAATTACCCGTTTGAGACAT
TATTGAGCCGTTGGTTGGTCACGGCGGTATTTGTCTTGGTGGCCGTTTGTTGGCTCAGCCTGAAAGTCATGAGGCGAGTA
CAACACCTGGAAAAACTCCAACTGCAAACGAAAATTCAGCTCGACGACCCCGTCAGTGCTGATATCGAGCAACAAAACCA
CTACCTCAATGGCTGGAAGCACCAACTTCAGCGCCATTTGAACACCCCGGAATATCTGTATCGCCTGCCCTGGTACATGG
TCATTGGTGCGCGCAATAGCGGCAAAAGTACACTGATCAAAGAAGGGTATAAACTGACAGAGATCTCCGCATCCGAGCGG
CTCCATGCGGAAGACGCAGCAGATCTGCGCGTCCGCTGCTGGTTGGGGGAACAAGCGGTTATTATCGATCCTGCGGGGGT
GCTGATTGAACAACCTACGACACCGATCGCGGGCAAAGCATCACTCAACAGCCGCTTATGGCAAAGTCTATTATCCTGGC
TGATTGAACAGCGCCAGCGTCAGCCGCTAAACGGCATTATTCTCACCGTCGATCTTCATCAGATGATGACCGCGAATAAA
GCGCAGCGGGAGACTTACGTCGCTGATATTCATCAACGGCTGCAAGAGATACGGCTGTCTTTGCACAGCCAGGTGCCGCT
GTATGTGGTGTTCACCAAAATGGACCTGCTGTACGGCTTCGAGGCCATGTACCAATCGCTGGATAAAGCCGAACGTGAAG
CGGTTCTGGGGGTGACGTTCAGCCTCAATGCGGCGGATCCGGACGTGTGGCGGACGGAGTTGAAACAGTTCTGGCAGCAA
TGGGTCGCACAACTGAATGGCGCGATGCCGGACATGATGCTGAACAGTGTGGATGCCGGGCAGCGTAGCCAGTTGTTTAG
CTTCACTCGCCAGATGCAGGGCCTGCACGATTACGTCGTGCAACTGCTGGAAGGCATTCTGTACCGTGGAGAACATGCCC
AGCCGCTGTTACGGGGGGTTTATCTCACGTCTGCCCAGCAACGCGGGCAAATGGACGATATCTTTACCCAATCTGCCGCG
GTGCAATATCACCTTGCGCCACAGGCCTTCCCGACCTGGCCGGTCTCGGATACGACGCCGTATTTTACCAAAGCGCTGTT
TAACCAGGTGCTATTGGCCGAACCCAATCTGGCCGGAGAGAACGGTATCTGGCTGCAAAAAACGAGAAAGCGAATGTTCA
TTTTCTCGGGGGTGGGTGCCCTGGCCGCGCTGACCTTATGGGGCTACTGGCACTACTATCACCAGCTTAACTACCGGGCT
GGCGAAGAGGTATTAACCCAGGCAAAAACCTTCTTATCGATCCCACCGCCAGAAGGCGATGACCGTTATGGCAATCTGCA
ACTGCCGCTGCTAAACCCCATCCGTGACGCCACGCTGGCTTACGGTAATTACCATGAACGCAGCCCGTTCCTGGCGGATA
TGGGGTTATATCAGGGCAATAATATCGGGCCTTATGTCGAAAGCACTTACTTGCAACTCCTACAGCAACGTTTTGTCCCG
GCACTGATGAGCGGGCTGTTAGAACAACTGAACGCCGCGCCGAAGGGCAGTGAAGAGAAACTGGAAATTCTGCGGGTGAT
GCGGATGTTGGAAGACGGCAGTGGCCGCAATGCCGCGCTGGTTGAACAATATATGAGCCACCGCTGGAGCCAACAATTCA
ACGGCCAGCGCGAGTTGCAGGAGCAACTGTCGAGCCACCTGAACTACGCACTGAAACACACCGACTGGCACGGCGCACGG
GAAAGTGGCGATCAATATGCGATCAAGAGCTTTGTTCCGTACCTCCGCCCGATCCAGTCAGCGCAGCAAGAGTTGAGCAA
ACTCTCGATCTACCAACGGGTGTATCAGAACCTGCGGATCAAAGCACAGGATGCGTTGCCGCCCGCGCTCGATTTGCGCG
ATCAGATCGGCGCAAGTTTTGACGACATCTTTGTCTCCGGTAACGATCGCCTGCTGGTGATCCCGCAATTCCTGACCCGT
AGCGGCTTACAGAGTTACTTCATCAAACAGAACGATCAACTGGTTGATCTCACGGTGATGGACAGTTGGGTACTTAATCT
CACCAAGAACGTCGAATACAGCGAGGCAGACCGCAAAGAGATCCATCGCCAGGTGACCGAACAGTATCTTGGCGATTATA
CCGCCACCTGGCGTGCGGCTATGAATAACCTGTCGGTCAGTGATTTTGAAGGCTTGCCACAGGCGATCAGCGCCATTGAA
CAGGTGATCAGCGGGGAACAACCTTTCCGCCGTGCACTGCAAACGCTGAGTGACAACACCCGCTTGCCGGTTATCTCGGA
TCTGATCCCCGCGAAGGAGCAGCAAGAGCTGCTGCAAAAACCCGATTACCTGCTGCTGACCCGCATCAACCGTGAGTTCT
CCCCCGAAACGGCGGTGCTGGTGGAGAATGGCGATAAAGGCAGCGTGATCCAAAGTGTTTACCAAAAACTGACCGAGCTA
CACCGCTATCTGTTGGCGATCCAAAACTCGCCCGCGCCGGGCAAAGCGGCGTTGAAGGCGGTGCAATTACGTCTGGATCA
AAACAACAGTGATCCGATTTTTGAAGTCCAGCAACTGGCTAAAAACCTGCCGGAGCCGCTAAACCGTTGGGTGGGCGAAC
TGGCAGAGCAAGCCTGGCGGGTGGTGATGATGGAGGCGATCCAGTCACTGGAAGTGGAGTGGAATGAGACGGTGATCAAA
CAGTATCAAACCTACCTGGCCGGACGTTATCCCTTCGATCCTCACGCGAAACAGGATGTACCACTCAGTGAGTTTGAACG
CTTCTTCGGGCCGAAAGGCACGCTCGATGCATTCTATCAGCAGAACCTGAAACCGTTTGTCGAAAACAACCTGACCGGTG
GCAGCGATGGCGAATTGCTGATCCGGCCTGATGTGTTACAGCAACTGGCGCAGGCACGGAAAATTCGCGACACCTTCTTC
TCGGCCCAAAACGGCCTGGGCACACAGTTTGCGATTGAACCGGTGCTGTTAAGTGGCAACAAGCGCCGCAGCGTATTGAA
TCTGGATGGGCAATTACTGGATTACGCCCATGGCCGCAGCGGCGTAGTGCATCTGGTTTGGCCAAACTCGATGCGTGCAG
GAGTGGAAAGCAAACTGACGTTAGTCCCGGATGAGAGCGGCAAATCACCGCGCACCCTCAGCTTCAGCGGTCCTTGGGCG
CAGTTGCGGCTGATCAACGCCGGTGAACTGACCAATGTGGGCACCAACTCCTTCGATGTCCGCTTCAAGGTTGATGGCGG
CGAGATGACGTACCGCATCTTTGTTGATGAATCCGACAACCCATTCGCGGGCGGTTTGTTCAGTAAATTCAGTCTGCCAG
ACACTCTGTATTGA