Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   R8623_RS09745 Genome accession   NZ_AP026928
Coordinates   1878486..1878812 (-) Length   108 a.a.
NCBI ID   WP_000738625.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1873486..1883812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS09700 (PC0401_18720) rnpA 1873511..1873882 (-) 372 WP_000739247.1 ribonuclease P protein component -
  R8623_RS09705 - 1873899..1874030 (-) 132 WP_000768904.1 hypothetical protein -
  R8623_RS09710 (PC0401_18730) - 1874031..1875221 (-) 1191 WP_000167765.1 acetate kinase -
  R8623_RS09715 (PC0401_18740) comYH 1875272..1876225 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  R8623_RS09720 (PC0401_18750) - 1876286..1876873 (-) 588 WP_000679779.1 class I SAM-dependent methyltransferase -
  R8623_RS09725 (PC0401_18760) comGG/cglG 1876976..1877422 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8623_RS09730 comGF/cglF 1877400..1877861 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8623_RS09735 (PC0401_18780) comGE/cglE 1877824..1878126 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8623_RS09740 (PC0401_18790) comGD/cglD 1878089..1878493 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8623_RS09745 (PC0401_18800) comGC/cglC 1878486..1878812 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  R8623_RS09750 (PC0401_18810) comGB/cglB 1878814..1879830 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8623_RS09755 (PC0401_18820) comGA/cglA/cilD 1879778..1880719 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  R8623_RS09760 (PC0401_18830) - 1880753..1881157 (-) 405 WP_317649603.1 DUF1033 family protein -
  R8623_RS09765 (PC0401_18840) - 1881308..1882366 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  R8623_RS09770 (PC0401_18850) nagA 1882529..1883680 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12143.28 Da        Isoelectric Point: 10.0055

>NTDB_id=98621 R8623_RS09745 WP_000738625.1 1878486..1878812(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700406]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=98621 R8623_RS09745 WP_000738625.1 1878486..1878812(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700406]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae Rx1

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae D39

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae R6

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae TIGR4

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

92.857

90.741

0.843
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comYC Streptococcus suis isolate S10

64.773

81.481

0.528
  comGC Staphylococcus aureus MW2

47.674

79.63

0.38
  comGC Staphylococcus aureus N315

47.674

79.63

0.38

Multiple sequence alignment