Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8623_RS09715 Genome accession   NZ_AP026928
Coordinates   1875272..1876225 (-) Length   317 a.a.
NCBI ID   WP_000345122.1    Uniprot ID   A0A0I7TJC1
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1870272..1881225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS09685 (PC0401_18680) - 1871031..1871654 (-) 624 WP_000932659.1 hypothetical protein -
  R8623_RS09690 (PC0401_18690) jag 1871705..1872691 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  R8623_RS09695 - 1872710..1873536 (-) 827 Protein_1883 membrane protein insertase YidC -
  R8623_RS09700 (PC0401_18720) rnpA 1873511..1873882 (-) 372 WP_000739247.1 ribonuclease P protein component -
  R8623_RS09705 - 1873899..1874030 (-) 132 WP_000768904.1 hypothetical protein -
  R8623_RS09710 (PC0401_18730) - 1874031..1875221 (-) 1191 WP_000167765.1 acetate kinase -
  R8623_RS09715 (PC0401_18740) comYH 1875272..1876225 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  R8623_RS09720 (PC0401_18750) - 1876286..1876873 (-) 588 WP_000679779.1 class I SAM-dependent methyltransferase -
  R8623_RS09725 (PC0401_18760) comGG/cglG 1876976..1877422 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8623_RS09730 comGF/cglF 1877400..1877861 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8623_RS09735 (PC0401_18780) comGE/cglE 1877824..1878126 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8623_RS09740 (PC0401_18790) comGD/cglD 1878089..1878493 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8623_RS09745 (PC0401_18800) comGC/cglC 1878486..1878812 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  R8623_RS09750 (PC0401_18810) comGB/cglB 1878814..1879830 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8623_RS09755 (PC0401_18820) comGA/cglA/cilD 1879778..1880719 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  R8623_RS09760 (PC0401_18830) - 1880753..1881157 (-) 405 WP_317649603.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35745.94 Da        Isoelectric Point: 4.2706

>NTDB_id=98616 R8623_RS09715 WP_000345122.1 1875272..1876225(-) (comYH) [Streptococcus pneumoniae strain PZ900700406]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSNLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=98616 R8623_RS09715 WP_000345122.1 1875272..1876225(-) (comYH) [Streptococcus pneumoniae strain PZ900700406]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTTATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTAATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0I7TJC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

53.994

98.738

0.533
  comYH Streptococcus mutans UA159

53.674

98.738

0.53

Multiple sequence alignment