Detailed information NTG0098618

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R8623_RS09730
• Genome accession: NZ_AP026928
• Coordinates: 1877400..1877861 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700406
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1872400..1882861

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8623_RS09695	-	1872710..1873536 (-)	827	Protein_1883	membrane protein insertase YidC	-
R8623_RS09700 (PC0401_18720)	rnpA	1873511..1873882 (-)	372	WP_000739247.1	ribonuclease P protein component	-
R8623_RS09705	-	1873899..1874030 (-)	132	WP_000768904.1	hypothetical protein	-
R8623_RS09710 (PC0401_18730)	-	1874031..1875221 (-)	1191	WP_000167765.1	acetate kinase	-
R8623_RS09715 (PC0401_18740)	comYH	1875272..1876225 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
R8623_RS09720 (PC0401_18750)	-	1876286..1876873 (-)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
R8623_RS09725 (PC0401_18760)	comGG/cglG	1876976..1877422 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8623_RS09730	comGF/cglF	1877400..1877861 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8623_RS09735 (PC0401_18780)	comGE/cglE	1877824..1878126 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8623_RS09740 (PC0401_18790)	comGD/cglD	1878089..1878493 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8623_RS09745 (PC0401_18800)	comGC/cglC	1878486..1878812 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
R8623_RS09750 (PC0401_18810)	comGB/cglB	1878814..1879830 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8623_RS09755 (PC0401_18820)	comGA/cglA/cilD	1879778..1880719 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
R8623_RS09760 (PC0401_18830)	-	1880753..1881157 (-)	405	WP_317649603.1	DUF1033 family protein	-
R8623_RS09765 (PC0401_18840)	-	1881308..1882366 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=98618 R8623_RS09730 WP_000250539.1 1877400..1877861(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700406]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=98618 R8623_RS09730 WP_000250539.1 1877400..1877861(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700406]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915