Detailed information NTG0912562

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: U0N78_RS00765
• Genome accession: NZ_CP140109
• Coordinates: 127885..128166 (+)
• Length: 93 a.a.
• NCBI ID: WP_043026803.1
• Uniprot ID: A0A0Z8IB74
• Organism: Streptococcus suis strain 2022WUSS148
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 122885..133166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0N78_RS00745 (U0N78_00745)	-	124444..124803 (+)	360	WP_043026811.1	DUF1033 family protein	-
U0N78_RS00750 (U0N78_00750)	-	124948..125898 (-)	951	WP_043026809.1	S66 family peptidase	-
U0N78_RS00755 (U0N78_00755)	comYA	125984..126934 (+)	951	WP_043026808.1	competence type IV pilus ATPase ComGA	Machinery gene
U0N78_RS00760 (U0N78_00760)	comYB	126846..127883 (+)	1038	WP_043026806.1	competence type IV pilus assembly protein ComGB	Machinery gene
U0N78_RS00765 (U0N78_00765)	comYC	127885..128166 (+)	282	WP_043026803.1	competence type IV pilus major pilin ComGC	Machinery gene
U0N78_RS00770 (U0N78_00770)	comGD	128147..128554 (+)	408	WP_043026801.1	competence type IV pilus minor pilin ComGD	-
U0N78_RS00775 (U0N78_00775)	comGE	128598..128735 (+)	138	Protein_118	competence system putative prepilin ComGE	-
U0N78_RS00780 (U0N78_00780)	comGF/cglF	128805..129239 (+)	435	WP_043026797.1	competence type IV pilus minor pilin ComGF	Machinery gene
U0N78_RS00785 (U0N78_00785)	comGG	129217..129744 (+)	528	WP_043026795.1	competence type IV pilus minor pilin ComGG	-
U0N78_RS00790 (U0N78_00790)	comYH	129801..130754 (+)	954	WP_043026794.1	class I SAM-dependent methyltransferase	Machinery gene
U0N78_RS00795 (U0N78_00795)	-	130805..131992 (+)	1188	WP_043026792.1	acetate kinase	-
U0N78_RS00800 (U0N78_00800)	-	132307..132858 (+)	552	WP_043026790.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10460.40 Da
• Isoelectric Point: 8.4204

>NTDB_id=912562 U0N78_RS00765 WP_043026803.1 127885..128166(+) (comYC) [Streptococcus suis strain 2022WUSS148]
MKKLLKLKKKAFTLVEMLVVLGIISLLLLIFVPNLSQQKDAIQEKGNAAVVKVVESQMELYELEHDEEATVADLQAKGYI
TDKQAEQYAKAKK

Nucleotide

• Length: 282 bp

>NTDB_id=912562 U0N78_RS00765 WP_043026803.1 127885..128166(+) (comYC) [Streptococcus suis strain 2022WUSS148]
ATGAAAAAATTGTTGAAATTAAAAAAGAAAGCTTTCACTCTGGTGGAAATGTTAGTTGTTTTGGGTATTATTAGCCTGCT
CTTGCTCATTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCCATTCAGGAGAAAGGGAATGCAGCTGTTGTCAAAGTAG
TGGAGAGTCAGATGGAGCTCTATGAATTGGAACATGACGAGGAAGCAACGGTGGCAGATTTGCAGGCGAAAGGCTATATT
ACTGATAAACAAGCGGAGCAGTATGCTAAGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0Z8IB74

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	88.172	100	0.882
comGC/cglC	Streptococcus pneumoniae TIGR4	63.043	98.925	0.624
comGC/cglC	Streptococcus pneumoniae Rx1	63.043	98.925	0.624
comGC/cglC	Streptococcus pneumoniae D39	63.043	98.925	0.624
comGC/cglC	Streptococcus pneumoniae R6	63.043	98.925	0.624
comGC/cglC	Streptococcus mitis NCTC 12261	63.043	98.925	0.624
comGC/cglC	Streptococcus mitis SK321	63.043	98.925	0.624
comYC	Streptococcus gordonii str. Challis substr. CH1	64.045	95.699	0.613
comYC	Streptococcus mutans UA140	59.091	94.624	0.559
comYC	Streptococcus mutans UA159	59.091	94.624	0.559
comGC	Lactococcus lactis subsp. cremoris KW2	55.682	94.624	0.527
comGC	Staphylococcus aureus MW2	47.826	98.925	0.473
comGC	Staphylococcus aureus N315	47.826	98.925	0.473
comGC	Bacillus subtilis subsp. subtilis str. 168	46.667	80.645	0.376