Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   U0N78_RS00760 Genome accession   NZ_CP140109
Coordinates   126846..127883 (+) Length   345 a.a.
NCBI ID   WP_043026806.1    Uniprot ID   -
Organism   Streptococcus suis strain 2022WUSS148     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 121846..132883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS00745 (U0N78_00745) - 124444..124803 (+) 360 WP_043026811.1 DUF1033 family protein -
  U0N78_RS00750 (U0N78_00750) - 124948..125898 (-) 951 WP_043026809.1 S66 family peptidase -
  U0N78_RS00755 (U0N78_00755) comYA 125984..126934 (+) 951 WP_043026808.1 competence type IV pilus ATPase ComGA Machinery gene
  U0N78_RS00760 (U0N78_00760) comYB 126846..127883 (+) 1038 WP_043026806.1 competence type IV pilus assembly protein ComGB Machinery gene
  U0N78_RS00765 (U0N78_00765) comYC 127885..128166 (+) 282 WP_043026803.1 competence type IV pilus major pilin ComGC Machinery gene
  U0N78_RS00770 (U0N78_00770) comGD 128147..128554 (+) 408 WP_043026801.1 competence type IV pilus minor pilin ComGD -
  U0N78_RS00775 (U0N78_00775) comGE 128598..128735 (+) 138 Protein_118 competence system putative prepilin ComGE -
  U0N78_RS00780 (U0N78_00780) comGF/cglF 128805..129239 (+) 435 WP_043026797.1 competence type IV pilus minor pilin ComGF Machinery gene
  U0N78_RS00785 (U0N78_00785) comGG 129217..129744 (+) 528 WP_043026795.1 competence type IV pilus minor pilin ComGG -
  U0N78_RS00790 (U0N78_00790) comYH 129801..130754 (+) 954 WP_043026794.1 class I SAM-dependent methyltransferase Machinery gene
  U0N78_RS00795 (U0N78_00795) - 130805..131992 (+) 1188 WP_043026792.1 acetate kinase -
  U0N78_RS00800 (U0N78_00800) - 132307..132858 (+) 552 WP_043026790.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38980.93 Da        Isoelectric Point: 8.5872

>NTDB_id=912561 U0N78_RS00760 WP_043026806.1 126846..127883(+) (comYB) [Streptococcus suis strain 2022WUSS148]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLGHIQSYLENVSKVRKKLIEVATYPVILLAFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKFIQIYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYDFFKRELSLIAEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=912561 U0N78_RS00760 WP_043026806.1 126846..127883(+) (comYB) [Streptococcus suis strain 2022WUSS148]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATCTGGGAGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGATGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCGGATTTGCGTTTTTCAGATGCGGTGGTCACGCAAGTAGCTCTGGCAGAAGTTCATGGCAATACCAGTCTGAGTTTGGG
CCATATTCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCAGTTATACTGC
TTGCTTTTCTTCTTTTGATTATGTTGGGTTTGAAAAATTACCTTCTGCCCCAGTTGGAGGAAGGTAATGCAGCGACTATG
CTGATAAATCATCTGCCGACTATCTTCTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATCAAGGTCTTTTCCTGCTTAGCTGCTCTGCCATTTTTCGGAAAATTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAGGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAGGAG
CAGCAGTCGCAGCTCTTTCGAGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
TAAGACCTACGACTTTTTTAAGCGGGAGCTGAGTTTGATTGCCGAGTATGGTCAGGTCAAGTCCAAGTTGGGGAGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

64.035

99.13

0.635
  comGB/cglB Streptococcus mitis NCTC 12261

60.896

97.101

0.591
  comGB/cglB Streptococcus mitis SK321

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae R6

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae TIGR4

60.299

97.101

0.586
  comYB Streptococcus mutans UA159

58.651

98.841

0.58
  comYB Streptococcus mutans UA140

58.651

98.841

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

97.681

0.499