Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   U0N78_RS00755 Genome accession   NZ_CP140109
Coordinates   125984..126934 (+) Length   316 a.a.
NCBI ID   WP_043026808.1    Uniprot ID   -
Organism   Streptococcus suis strain 2022WUSS148     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 120984..131934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS00745 (U0N78_00745) - 124444..124803 (+) 360 WP_043026811.1 DUF1033 family protein -
  U0N78_RS00750 (U0N78_00750) - 124948..125898 (-) 951 WP_043026809.1 S66 family peptidase -
  U0N78_RS00755 (U0N78_00755) comYA 125984..126934 (+) 951 WP_043026808.1 competence type IV pilus ATPase ComGA Machinery gene
  U0N78_RS00760 (U0N78_00760) comYB 126846..127883 (+) 1038 WP_043026806.1 competence type IV pilus assembly protein ComGB Machinery gene
  U0N78_RS00765 (U0N78_00765) comYC 127885..128166 (+) 282 WP_043026803.1 competence type IV pilus major pilin ComGC Machinery gene
  U0N78_RS00770 (U0N78_00770) comGD 128147..128554 (+) 408 WP_043026801.1 competence type IV pilus minor pilin ComGD -
  U0N78_RS00775 (U0N78_00775) comGE 128598..128735 (+) 138 Protein_118 competence system putative prepilin ComGE -
  U0N78_RS00780 (U0N78_00780) comGF/cglF 128805..129239 (+) 435 WP_043026797.1 competence type IV pilus minor pilin ComGF Machinery gene
  U0N78_RS00785 (U0N78_00785) comGG 129217..129744 (+) 528 WP_043026795.1 competence type IV pilus minor pilin ComGG -
  U0N78_RS00790 (U0N78_00790) comYH 129801..130754 (+) 954 WP_043026794.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35487.24 Da        Isoelectric Point: 5.0469

>NTDB_id=912560 U0N78_RS00755 WP_043026808.1 125984..126934(+) (comYA) [Streptococcus suis strain 2022WUSS148]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDVAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFANGDYQNHSADQWNEQIDRLFAAGHISLRQAETEKITLGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=912560 U0N78_RS00755 WP_043026808.1 125984..126934(+) (comYA) [Streptococcus suis strain 2022WUSS148]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTACCATCGTATCATGGACGAGCGGGAGTTTGTGCAAGACGTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATTGAAGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATTAAACTGTCCCTCCGTCATCGACCAGACCTGCTCATCATCGGTGAAATTCGGGATGCAGAAACGG
CACGGGCGGTCATCAGGGCCAGTCTGACAGGAGCGACGGTCTTCTCAACGGTTCACGCAAGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTGGAATTGGGTGTCAGCCCTGAAGAGCTAAACAATGCCCTTCAAGGCATTGCCTATCAACGATTGATTGG
GGGAGGAGGTGTAGTGGATTTTGCAAATGGAGACTACCAAAACCATTCCGCAGACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

98.418

0.646
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538