Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU38_RS05350 Genome accession   NZ_CP148583
Coordinates   1073010..1073666 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1322HEC0001     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068010..1078666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU38_RS05320 (WHU38_05320) yecA 1069262..1069927 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  WHU38_RS05340 (WHU38_05340) pgsA 1070576..1071124 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU38_RS05345 (WHU38_05345) uvrC 1071181..1073013 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU38_RS05350 (WHU38_05350) letA 1073010..1073666 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU38_RS05355 (WHU38_05355) - 1073808..1073879 (+) 72 Protein_1055 transcriptional regulator -
  WHU38_RS05360 (WHU38_05360) yecU 1073962..1074138 (+) 177 WP_000590347.1 protein YecU -
  WHU38_RS05365 (WHU38_05365) yecF 1074125..1074349 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU38_RS05370 (WHU38_05370) sdiA 1074416..1075138 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  WHU38_RS05375 (WHU38_05375) tcyN 1075368..1076120 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU38_RS05380 (WHU38_05380) tcyL 1076117..1076785 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU38_RS05385 (WHU38_05385) dcyD 1076800..1077786 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=873317 WHU38_RS05350 WP_000611335.1 1073010..1073666(-) (letA) [Escherichia coli strain Z1322HEC0001]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=873317 WHU38_RS05350 WP_000611335.1 1073010..1073666(-) (letA) [Escherichia coli strain Z1322HEC0001]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486