Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   PW252_RS00685 Genome accession   NZ_CP118735
Coordinates   109121..110071 (+) Length   316 a.a.
NCBI ID   WP_248049581.1    Uniprot ID   A0AA96VMF4
Organism   Streptococcus iners strain 29887     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 104121..115071
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS00670 (PW252_00670) - 106108..106485 (+) 378 WP_172049590.1 DUF1033 family protein -
  PW252_RS00675 (PW252_00675) - 106605..107948 (-) 1344 Protein_99 IS1182 family transposase -
  PW252_RS00680 (PW252_00680) - 108086..109036 (-) 951 WP_248049579.1 S66 peptidase family protein -
  PW252_RS00685 (PW252_00685) comYA 109121..110071 (+) 951 WP_248049581.1 competence type IV pilus ATPase ComGA Machinery gene
  PW252_RS00690 (PW252_00690) comYB 109983..111020 (+) 1038 WP_248049583.1 competence type IV pilus assembly protein ComGB Machinery gene
  PW252_RS00695 (PW252_00695) comYC 111022..111303 (+) 282 WP_248049584.1 competence type IV pilus major pilin ComGC Machinery gene
  PW252_RS00700 (PW252_00700) comGD 111284..111691 (+) 408 WP_248049586.1 competence type IV pilus minor pilin ComGD -
  PW252_RS00705 (PW252_00705) comYE 111663..111956 (+) 294 WP_248049588.1 competence type IV pilus minor pilin ComGE Machinery gene
  PW252_RS00710 (PW252_00710) comGF/cglF 111943..112377 (+) 435 WP_248049590.1 competence type IV pilus minor pilin ComGF Machinery gene
  PW252_RS00715 (PW252_00715) comGG 112355..112873 (+) 519 WP_248049592.1 competence type IV pilus minor pilin ComGG -
  PW252_RS00720 (PW252_00720) comYH 112927..113880 (+) 954 WP_248049593.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35568.33 Da        Isoelectric Point: 5.4629

>NTDB_id=794716 PW252_RS00685 WP_248049581.1 109121..110071(+) (comYA) [Streptococcus iners strain 29887]
MIQEKARKLIEEAVADRVSDIYLVPRGQDYQVYHRIMDEREFVHDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGNGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVRPEELNNALQGIAYQRLIGGGGVVDFANGDYQNHSANQWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=794716 PW252_RS00685 WP_248049581.1 109121..110071(+) (comYA) [Streptococcus iners strain 29887]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAGGACTACCAAGTCTACCATCGCATCATGGACGAACGGGAGTTTGTGCACGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTCTTAGCAGGTTTAAATGTCGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAACGGCGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCTGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACTATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTCCATGCAAGGTCTATTTCAGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGGCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTGATAGG
GGGAGGAGGTGTAGTGGATTTTGCAAATGGAGACTACCAAAACCATTCCGCAAACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

67.742

98.101

0.665
  comYA Streptococcus mutans UA159

67.203

98.418

0.661
  comYA Streptococcus mutans UA140

67.203

98.418

0.661
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

52.997

100

0.532
  comGA Bacillus subtilis subsp. subtilis str. 168

39

94.937

0.37