Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   PW252_RS00690 Genome accession   NZ_CP118735
Coordinates   109983..111020 (+) Length   345 a.a.
NCBI ID   WP_248049583.1    Uniprot ID   -
Organism   Streptococcus iners strain 29887     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 104983..116020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS00670 (PW252_00670) - 106108..106485 (+) 378 WP_172049590.1 DUF1033 family protein -
  PW252_RS00675 (PW252_00675) - 106605..107948 (-) 1344 Protein_99 IS1182 family transposase -
  PW252_RS00680 (PW252_00680) - 108086..109036 (-) 951 WP_248049579.1 S66 peptidase family protein -
  PW252_RS00685 (PW252_00685) comYA 109121..110071 (+) 951 WP_248049581.1 competence type IV pilus ATPase ComGA Machinery gene
  PW252_RS00690 (PW252_00690) comYB 109983..111020 (+) 1038 WP_248049583.1 competence type IV pilus assembly protein ComGB Machinery gene
  PW252_RS00695 (PW252_00695) comYC 111022..111303 (+) 282 WP_248049584.1 competence type IV pilus major pilin ComGC Machinery gene
  PW252_RS00700 (PW252_00700) comGD 111284..111691 (+) 408 WP_248049586.1 competence type IV pilus minor pilin ComGD -
  PW252_RS00705 (PW252_00705) comYE 111663..111956 (+) 294 WP_248049588.1 competence type IV pilus minor pilin ComGE Machinery gene
  PW252_RS00710 (PW252_00710) comGF/cglF 111943..112377 (+) 435 WP_248049590.1 competence type IV pilus minor pilin ComGF Machinery gene
  PW252_RS00715 (PW252_00715) comGG 112355..112873 (+) 519 WP_248049592.1 competence type IV pilus minor pilin ComGG -
  PW252_RS00720 (PW252_00720) comYH 112927..113880 (+) 954 WP_248049593.1 class I SAM-dependent methyltransferase Machinery gene
  PW252_RS00725 (PW252_00725) - 113930..115117 (+) 1188 WP_105125239.1 acetate kinase -
  PW252_RS00730 (PW252_00730) - 115375..115926 (+) 552 WP_105125238.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38993.88 Da        Isoelectric Point: 9.2859

>NTDB_id=794717 PW252_RS00690 WP_248049583.1 109983..111020(+) (comYB) [Streptococcus iners strain 29887]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTSKIKAFSRLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFWEIGQDLEQSLSNGRDFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEEFFSRVNRAMHLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=794717 PW252_RS00690 WP_248049583.1 109983..111020(+) (comYB) [Streptococcus iners strain 29887]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAACTGTTTAACAATCTCTTTGCCAGCGGTTTTCATCTGGGGGAGATTGTTGATTTTCTTAAAC
GCAGTCAGCTTTTGGCAGACCCATATACCCAAGTTTTATCCGATGGTCTTCTTGCAGGCAAACCTTTTTCAAGTTTGCTG
GCGGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCACTGGCAGAAGTTCATGGCAATACCAGTCTGAGTTTAAG
TCATATTCAGTCCTATCTGGAAAACGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCAGTTATCTTGC
TAGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAACTACCTTTTGCCCCAGTTGGAGGAAGGCAATGCAGCGACCGTG
CTAATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGCCTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACTAGCAAAATCAAAGCATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCTAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCCTGATGCAGGAA
CAACAATCTCAGCTCTTTTGGGAGATTGGTCAGGACTTGGAGCAGTCGCTTTCCAATGGACGGGATTTTCACGAACACAT
CAAGACCTACGCCTTTTTTAAGCGGGAGTTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAATTAGGGAGCGAGT
TGACAGTCTATGCAGCTGAGTGTTGGGAGGAATTTTTCTCTCGGGTCAATAGAGCCATGCATCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTTATCTACGCAGCCATGTTGTTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comGB/cglB Streptococcus mitis SK321

60.896

97.101

0.591
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae D39

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae R6

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae TIGR4

60.597

97.101

0.588
  comYB Streptococcus mutans UA140

58.309

99.42

0.58
  comYB Streptococcus mutans UA159

58.309

99.42

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493