Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   PW252_RS00705 Genome accession   NZ_CP118735
Coordinates   111663..111956 (+) Length   97 a.a.
NCBI ID   WP_248049588.1    Uniprot ID   A0AA97A3S7
Organism   Streptococcus iners strain 29887     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 106663..116956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS00680 (PW252_00680) - 108086..109036 (-) 951 WP_248049579.1 S66 peptidase family protein -
  PW252_RS00685 (PW252_00685) comYA 109121..110071 (+) 951 WP_248049581.1 competence type IV pilus ATPase ComGA Machinery gene
  PW252_RS00690 (PW252_00690) comYB 109983..111020 (+) 1038 WP_248049583.1 competence type IV pilus assembly protein ComGB Machinery gene
  PW252_RS00695 (PW252_00695) comYC 111022..111303 (+) 282 WP_248049584.1 competence type IV pilus major pilin ComGC Machinery gene
  PW252_RS00700 (PW252_00700) comGD 111284..111691 (+) 408 WP_248049586.1 competence type IV pilus minor pilin ComGD -
  PW252_RS00705 (PW252_00705) comYE 111663..111956 (+) 294 WP_248049588.1 competence type IV pilus minor pilin ComGE Machinery gene
  PW252_RS00710 (PW252_00710) comGF/cglF 111943..112377 (+) 435 WP_248049590.1 competence type IV pilus minor pilin ComGF Machinery gene
  PW252_RS00715 (PW252_00715) comGG 112355..112873 (+) 519 WP_248049592.1 competence type IV pilus minor pilin ComGG -
  PW252_RS00720 (PW252_00720) comYH 112927..113880 (+) 954 WP_248049593.1 class I SAM-dependent methyltransferase Machinery gene
  PW252_RS00725 (PW252_00725) - 113930..115117 (+) 1188 WP_105125239.1 acetate kinase -
  PW252_RS00730 (PW252_00730) - 115375..115926 (+) 552 WP_105125238.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10839.80 Da        Isoelectric Point: 10.2073

>NTDB_id=794719 PW252_RS00705 WP_248049588.1 111663..111956(+) (comYE) [Streptococcus iners strain 29887]
MVAIRKQKNKAYILLESLVALATLVTICSLILTAVDAGRRRQAWELEQQEVLNLAQMAVQTEQDKLALNGVVVRVQRTAE
RVAVFHEGKEVLSVVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=794719 PW252_RS00705 WP_248049588.1 111663..111956(+) (comYE) [Streptococcus iners strain 29887]
GTGGTCGCTATAAGAAAACAGAAGAATAAGGCTTATATCTTGCTAGAAAGTTTAGTTGCCCTTGCGACCCTAGTGACCAT
TTGTAGCTTGATTTTGACTGCGGTGGATGCAGGTCGTAGGAGGCAGGCTTGGGAATTAGAACAACAGGAAGTTCTCAATC
TGGCTCAGATGGCCGTGCAGACCGAGCAAGATAAGCTAGCCTTAAACGGAGTTGTAGTCCGGGTTCAACGCACTGCGGAA
AGAGTTGCGGTTTTCCATGAAGGAAAGGAGGTTTTATCGGTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

54.639

100

0.546
  comYE Streptococcus mutans UA159

54.639

100

0.546
  comGE/cglE Streptococcus pneumoniae Rx1

39.13

94.845

0.371
  comGE/cglE Streptococcus pneumoniae D39

39.13

94.845

0.371
  comGE/cglE Streptococcus pneumoniae R6

39.13

94.845

0.371
  comGE/cglE Streptococcus pneumoniae TIGR4

39.13

94.845

0.371
  comGE/cglE Streptococcus mitis SK321

38.043

94.845

0.361
  comGE/cglE Streptococcus mitis NCTC 12261

38.043

94.845

0.361