Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQA32_RS11150 Genome accession   NZ_CP126926
Coordinates   2313886..2314542 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O2:K1:H5 strain APEC E19035     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2308886..2319542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA32_RS11120 (QQA32_11120) dcyD 2309765..2310751 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  QQA32_RS11125 (QQA32_11125) tcyL 2310766..2311434 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QQA32_RS11130 (QQA32_11130) tcyN 2311431..2312183 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQA32_RS11135 (QQA32_11135) sdiA 2312413..2313135 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  QQA32_RS11140 (QQA32_11140) yecF 2313203..2313427 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQA32_RS11145 (QQA32_11145) yecU 2313414..2313590 (-) 177 WP_001307856.1 protein YecU -
  QQA32_RS11150 (QQA32_11150) letA 2313886..2314542 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQA32_RS11155 (QQA32_11155) uvrC 2314539..2316371 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QQA32_RS11160 (QQA32_11160) pgsA 2316428..2316976 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQA32_RS11180 (QQA32_11180) yecA 2317625..2318290 (+) 666 WP_103433210.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=768511 QQA32_RS11150 WP_000611328.1 2313886..2314542(+) (letA) [Escherichia coli O2:K1:H5 strain APEC E19035]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=768511 QQA32_RS11150 WP_000611328.1 2313886..2314542(+) (letA) [Escherichia coli O2:K1:H5 strain APEC E19035]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482