Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EL271_RS10170 Genome accession   NZ_AP018937
Coordinates   1856984..1857310 (-) Length   108 a.a.
NCBI ID   WP_000738636.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HU-OH     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1851984..1862310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL271_RS10130 (SPOH_1882) rnpA 1852001..1852372 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EL271_RS12015 - 1852389..1852520 (-) 132 WP_000768904.1 hypothetical protein -
  EL271_RS10135 (SPOH_1883) - 1852521..1853711 (-) 1191 WP_000167765.1 acetate kinase -
  EL271_RS10140 (SPOH_1884) comYH 1853762..1854715 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  EL271_RS10145 - 1854776..1855370 (-) 595 Protein_1869 class I SAM-dependent methyltransferase -
  EL271_RS10150 (SPOH_1887) comGG/cglG 1855507..1855920 (-) 414 WP_050295052.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL271_RS10155 (SPOH_1888) comGF/cglF 1855898..1856359 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL271_RS10160 (SPOH_1889) comGE/cglE 1856322..1856624 (-) 303 WP_269471257.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL271_RS10165 (SPOH_1890) comGD/cglD 1856587..1856991 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL271_RS10170 (SPOH_1891) comGC/cglC 1856984..1857310 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  EL271_RS10175 (SPOH_1892) comGB/cglB 1857312..1858328 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL271_RS10180 (SPOH_1893) comGA/cglA/cilD 1858276..1859217 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  EL271_RS10185 (SPOH_1894) - 1859293..1859658 (-) 366 WP_000286415.1 DUF1033 family protein -
  EL271_RS10190 (SPOH_1895) - 1859809..1860867 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EL271_RS10195 (SPOH_1896) nagA 1861030..1862181 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12208.39 Da        Isoelectric Point: 10.0305

>NTDB_id=71902 EL271_RS10170 WP_000738636.1 1856984..1857310(-) (comGC/cglC) [Streptococcus pneumoniae strain HU-OH]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKE
DGRITEEQAKAYKEYNDKNVGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=71902 EL271_RS10170 WP_000738636.1 1856984..1857310(-) (comGC/cglC) [Streptococcus pneumoniae strain HU-OH]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGTGGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae Rx1

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae D39

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae R6

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

93.878

90.741

0.852
  comYC Streptococcus gordonii str. Challis substr. CH1

71.875

88.889

0.639
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment