Detailed information NTG0071899

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EL271_RS10155
• Genome accession: NZ_AP018937
• Coordinates: 1855898..1856359 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain HU-OH
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1850898..1861359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL271_RS10125 (SPOH_1881)	-	1851202..1852026 (-)	825	WP_001809383.1	membrane protein insertase YidC	-
EL271_RS10130 (SPOH_1882)	rnpA	1852001..1852372 (-)	372	WP_000739244.1	ribonuclease P protein component	-
EL271_RS12015	-	1852389..1852520 (-)	132	WP_000768904.1	hypothetical protein	-
EL271_RS10135 (SPOH_1883)	-	1852521..1853711 (-)	1191	WP_000167765.1	acetate kinase	-
EL271_RS10140 (SPOH_1884)	comYH	1853762..1854715 (-)	954	WP_000345099.1	class I SAM-dependent methyltransferase	Machinery gene
EL271_RS10145	-	1854776..1855370 (-)	595	Protein_1869	class I SAM-dependent methyltransferase	-
EL271_RS10150 (SPOH_1887)	comGG/cglG	1855507..1855920 (-)	414	WP_050295052.1	competence type IV pilus minor pilin ComGG	Machinery gene
EL271_RS10155 (SPOH_1888)	comGF/cglF	1855898..1856359 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL271_RS10160 (SPOH_1889)	comGE/cglE	1856322..1856624 (-)	303	WP_269471257.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL271_RS10165 (SPOH_1890)	comGD/cglD	1856587..1856991 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL271_RS10170 (SPOH_1891)	comGC/cglC	1856984..1857310 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
EL271_RS10175 (SPOH_1892)	comGB/cglB	1857312..1858328 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL271_RS10180 (SPOH_1893)	comGA/cglA/cilD	1858276..1859217 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
EL271_RS10185 (SPOH_1894)	-	1859293..1859658 (-)	366	WP_000286415.1	DUF1033 family protein	-
EL271_RS10190 (SPOH_1895)	-	1859809..1860867 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=71899 EL271_RS10155 WP_000250542.1 1855898..1856359(-) (comGF/cglF) [Streptococcus pneumoniae strain HU-OH]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=71899 EL271_RS10155 WP_000250542.1 1855898..1856359(-) (comGF/cglF) [Streptococcus pneumoniae strain HU-OH]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909