Detailed information NTG0714613

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: NQZ97_RS00850
• Genome accession: NZ_CP102136
• Coordinates: 142153..142434 (+)
• Length: 93 a.a.
• NCBI ID: WP_043026803.1
• Uniprot ID: A0A0Z8IB74
• Organism: Streptococcus suis strain M105052_S26
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 137153..147434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ97_RS00820 (NQZ97_00820)	-	137159..137479 (+)	321	WP_029173981.1	PTS sugar transporter subunit IIB	-
NQZ97_RS00825 (NQZ97_00825)	-	137483..137824 (+)	342	WP_105152398.1	PTS lactose/cellobiose transporter subunit IIA	-
NQZ97_RS00830 (NQZ97_00830)	-	137824..139179 (+)	1356	WP_105152397.1	PTS sugar transporter subunit IIC	-
NQZ97_RS00835 (NQZ97_00835)	-	139198..140166 (-)	969	WP_105152396.1	S66 peptidase family protein	-
NQZ97_RS00840 (NQZ97_00840)	comYA	140252..141202 (+)	951	WP_043026808.1	competence type IV pilus ATPase ComGA	Machinery gene
NQZ97_RS00845 (NQZ97_00845)	comYB	141114..142151 (+)	1038	WP_249338910.1	competence type IV pilus assembly protein ComGB	Machinery gene
NQZ97_RS00850 (NQZ97_00850)	comYC	142153..142434 (+)	282	WP_043026803.1	competence type IV pilus major pilin ComGC	Machinery gene
NQZ97_RS00855 (NQZ97_00855)	comGD	142415..142822 (+)	408	WP_105152395.1	competence type IV pilus minor pilin ComGD	-
NQZ97_RS00860 (NQZ97_00860)	comYE	142794..143087 (+)	294	WP_043026799.1	competence type IV pilus minor pilin ComGE	Machinery gene
NQZ97_RS00865 (NQZ97_00865)	comGF/cglF	143074..143508 (+)	435	WP_043026797.1	competence type IV pilus minor pilin ComGF	Machinery gene
NQZ97_RS00870 (NQZ97_00870)	comGG	143486..144013 (+)	528	WP_043026795.1	competence type IV pilus minor pilin ComGG	-
NQZ97_RS00875 (NQZ97_00875)	comYH	144070..145023 (+)	954	WP_256787745.1	class I SAM-dependent methyltransferase	Machinery gene
NQZ97_RS00880 (NQZ97_00880)	-	145074..146261 (+)	1188	WP_099871820.1	acetate kinase	-
NQZ97_RS00885 (NQZ97_00885)	-	146578..147129 (+)	552	WP_256787742.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10460.40 Da
• Isoelectric Point: 8.4204

>NTDB_id=714613 NQZ97_RS00850 WP_043026803.1 142153..142434(+) (comYC) [Streptococcus suis strain M105052_S26]
MKKLLKLKKKAFTLVEMLVVLGIISLLLLIFVPNLSQQKDAIQEKGNAAVVKVVESQMELYELEHDEEATVADLQAKGYI
TDKQAEQYAKAKK

Nucleotide

• Length: 282 bp

>NTDB_id=714613 NQZ97_RS00850 WP_043026803.1 142153..142434(+) (comYC) [Streptococcus suis strain M105052_S26]
ATGAAAAAATTGTTGAAATTAAAAAAGAAAGCTTTCACTCTGGTGGAAATGTTAGTTGTTTTGGGTATTATTAGCCTGCT
CTTGCTCATTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCCATTCAGGAGAAAGGGAATGCAGCTGTTGTCAAAGTAG
TGGAGAGTCAGATGGAGCTCTATGAATTGGAACATGACGAGGAAGCAACGGTGGCAGATTTGCAGGCGAAAGGCTATATT
ACTGATAAACAAGCGGAGCAGTATGCTAAGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0Z8IB74

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	88.172	100	0.882
comGC/cglC	Streptococcus pneumoniae TIGR4	63.043	98.925	0.624
comGC/cglC	Streptococcus pneumoniae Rx1	63.043	98.925	0.624
comGC/cglC	Streptococcus pneumoniae D39	63.043	98.925	0.624
comGC/cglC	Streptococcus pneumoniae R6	63.043	98.925	0.624
comGC/cglC	Streptococcus mitis NCTC 12261	63.043	98.925	0.624
comGC/cglC	Streptococcus mitis SK321	63.043	98.925	0.624
comYC	Streptococcus gordonii str. Challis substr. CH1	64.045	95.699	0.613
comYC	Streptococcus mutans UA140	59.091	94.624	0.559
comYC	Streptococcus mutans UA159	59.091	94.624	0.559
comGC	Lactococcus lactis subsp. cremoris KW2	55.682	94.624	0.527
comGC	Staphylococcus aureus MW2	47.826	98.925	0.473
comGC	Staphylococcus aureus N315	47.826	98.925	0.473
comGC	Bacillus subtilis subsp. subtilis str. 168	46.667	80.645	0.376