NTDB

Overview

Name	comGF/cglF	Type	Machinery gene
Locus tag	NQZ97_RS00865	Genome accession	NZ_CP102136
Coordinates	143074..143508 (+)	Length	144 a.a.
NCBI ID	WP_043026797.1	Uniprot ID	A0A0Z8IB52
Organism	Streptococcus suis strain M105052_S26
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 138074..148508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ97_RS00835 (NQZ97_00835)	-	139198..140166 (-)	969	WP_105152396.1	S66 peptidase family protein	-
NQZ97_RS00840 (NQZ97_00840)	comYA	140252..141202 (+)	951	WP_043026808.1	competence type IV pilus ATPase ComGA	Machinery gene
NQZ97_RS00845 (NQZ97_00845)	comYB	141114..142151 (+)	1038	WP_249338910.1	competence type IV pilus assembly protein ComGB	Machinery gene
NQZ97_RS00850 (NQZ97_00850)	comYC	142153..142434 (+)	282	WP_043026803.1	competence type IV pilus major pilin ComGC	Machinery gene
NQZ97_RS00855 (NQZ97_00855)	comGD	142415..142822 (+)	408	WP_105152395.1	competence type IV pilus minor pilin ComGD	-
NQZ97_RS00860 (NQZ97_00860)	comYE	142794..143087 (+)	294	WP_043026799.1	competence type IV pilus minor pilin ComGE	Machinery gene
NQZ97_RS00865 (NQZ97_00865)	comGF/cglF	143074..143508 (+)	435	WP_043026797.1	competence type IV pilus minor pilin ComGF	Machinery gene
NQZ97_RS00870 (NQZ97_00870)	comGG	143486..144013 (+)	528	WP_043026795.1	competence type IV pilus minor pilin ComGG	-
NQZ97_RS00875 (NQZ97_00875)	comYH	144070..145023 (+)	954	WP_256787745.1	class I SAM-dependent methyltransferase	Machinery gene
NQZ97_RS00880 (NQZ97_00880)	-	145074..146261 (+)	1188	WP_099871820.1	acetate kinase	-
NQZ97_RS00885 (NQZ97_00885)	-	146578..147129 (+)	552	WP_256787742.1	folate family ECF transporter S component	-
NQZ97_RS00890 (NQZ97_00890)	-	147183..148439 (+)	1257	WP_256787741.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

Download Length: 144 a.a. Molecular weight: 16462.85 Da Isoelectric Point: 8.8126

                                >NTDB_id=714615 NQZ97_RS00865 WP_043026797.1 143074..143508(+) (comGF/cglF) [Streptococcus suis strain M105052_S26]

MLKSKLPAFTLLECLVALIILSGSLLVFESLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE

QALAFGKSRSDDFRKTNDRGQGYQPMIYQVDSAAISQKNQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

Download Length: 435 bp

                                >NTDB_id=714615 NQZ97_RS00865 WP_043026797.1 143074..143508(+) (comGF/cglF) [Streptococcus suis strain M105052_S26]

TTGTTAAAAAGTAAACTTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCTTTAATCATCCTATCAGGAAGTCTTCTGGT

CTTTGAAAGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTACCAAGGTCAGACTGTTCAAAAGGAATGGTTGGTCTTCT

CTAGTCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGCGAA

CAGGCTTTGGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGCTATCAGCCCATGAT

TTATCAAGTAGACAGCGCAGCTATTTCCCAAAAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC

GGACGTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(37-134)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0Z8IB52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGF/cglF	Streptococcus pneumoniae D39	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae R6	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae TIGR4	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae Rx1	53.901	97.917	0.528
comYF	Streptococcus mutans UA140	49.306	100	0.493
comGF/cglF	Streptococcus mitis NCTC 12261	52.985	93.056	0.493
comYF	Streptococcus mutans UA159	48.611	100	0.486
comGF/cglF	Streptococcus mitis SK321	51.493	93.056	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	43.972	97.917	0.431

Detailed information NTG0714615