Detailed information NTG0705297

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: NLY75_RS00750
• Genome accession: NZ_CP100432
• Coordinates: 116002..116283 (+)
• Length: 93 a.a.
• NCBI ID: WP_011921720.1
• Uniprot ID: A0A0M9FL05
• Organism: Streptococcus suis T15
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 111002..121283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY75_RS00730 (NLY75_00730)	-	112665..113030 (+)	366	WP_023369079.1	DUF1033 family protein	-
NLY75_RS00735 (NLY75_00735)	-	113065..114015 (-)	951	WP_023369081.1	S66 peptidase family protein	-
NLY75_RS00740 (NLY75_00740)	comYA	114101..115051 (+)	951	WP_023369082.1	competence type IV pilus ATPase ComGA	Machinery gene
NLY75_RS00745 (NLY75_00745)	comYB	114963..116000 (+)	1038	WP_256786938.1	competence type IV pilus assembly protein ComGB	Machinery gene
NLY75_RS00750 (NLY75_00750)	comYC	116002..116283 (+)	282	WP_011921720.1	competence type IV pilus major pilin ComGC	Machinery gene
NLY75_RS00755 (NLY75_00755)	comGD	116264..116671 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	-
NLY75_RS00760 (NLY75_00760)	comYE	116643..116936 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
NLY75_RS00765 (NLY75_00765)	comGF/cglF	116923..117357 (+)	435	WP_023369086.1	competence type IV pilus minor pilin ComGF	Machinery gene
NLY75_RS00770 (NLY75_00770)	comGG	117335..117745 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	-
NLY75_RS00775 (NLY75_00775)	comYH	117802..118755 (+)	954	WP_011922562.1	class I SAM-dependent methyltransferase	Machinery gene
NLY75_RS00780 (NLY75_00780)	-	118805..119992 (+)	1188	WP_023369088.1	acetate kinase	-
NLY75_RS00785 (NLY75_00785)	-	120307..120858 (+)	552	WP_023369090.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10408.34 Da
• Isoelectric Point: 7.0117

>NTDB_id=705297 NLY75_RS00750 WP_011921720.1 116002..116283(+) (comYC) [Streptococcus suis T15]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDEEATVADLQAKGYI
TEKQAKQYATAKK

Nucleotide

• Length: 282 bp

>NTDB_id=705297 NLY75_RS00750 WP_011921720.1 116002..116283(+) (comYC) [Streptococcus suis T15]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTCTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGTCAGATGGAGCTCTATGAATTGGAACATGACGAGGAAGCAACGGTGGCAGATTTGCAGGCGAAAGGTTATATT
ACTGAAAAACAAGCAAAACAGTATGCTACGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0M9FL05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	100	100	1
comGC/cglC	Streptococcus mitis SK321	68.235	91.398	0.624
comGC/cglC	Streptococcus mitis NCTC 12261	68.235	91.398	0.624
comGC/cglC	Streptococcus pneumoniae D39	70.37	87.097	0.613
comGC/cglC	Streptococcus pneumoniae R6	70.37	87.097	0.613
comGC/cglC	Streptococcus pneumoniae TIGR4	70.37	87.097	0.613
comGC/cglC	Streptococcus pneumoniae Rx1	70.37	87.097	0.613
comYC	Streptococcus gordonii str. Challis substr. CH1	61.798	95.699	0.591
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	56.818	94.624	0.538
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398
comGC	Latilactobacillus sakei subsp. sakei 23K	43.75	86.022	0.376