Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   NLY75_RS00740 Genome accession   NZ_CP100432
Coordinates   114101..115051 (+) Length   316 a.a.
NCBI ID   WP_023369082.1    Uniprot ID   -
Organism   Streptococcus suis T15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 109101..120051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY75_RS00730 (NLY75_00730) - 112665..113030 (+) 366 WP_023369079.1 DUF1033 family protein -
  NLY75_RS00735 (NLY75_00735) - 113065..114015 (-) 951 WP_023369081.1 S66 peptidase family protein -
  NLY75_RS00740 (NLY75_00740) comYA 114101..115051 (+) 951 WP_023369082.1 competence type IV pilus ATPase ComGA Machinery gene
  NLY75_RS00745 (NLY75_00745) comYB 114963..116000 (+) 1038 WP_256786938.1 competence type IV pilus assembly protein ComGB Machinery gene
  NLY75_RS00750 (NLY75_00750) comYC 116002..116283 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  NLY75_RS00755 (NLY75_00755) comGD 116264..116671 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD -
  NLY75_RS00760 (NLY75_00760) comYE 116643..116936 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  NLY75_RS00765 (NLY75_00765) comGF/cglF 116923..117357 (+) 435 WP_023369086.1 competence type IV pilus minor pilin ComGF Machinery gene
  NLY75_RS00770 (NLY75_00770) comGG 117335..117745 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG -
  NLY75_RS00775 (NLY75_00775) comYH 117802..118755 (+) 954 WP_011922562.1 class I SAM-dependent methyltransferase Machinery gene
  NLY75_RS00780 (NLY75_00780) - 118805..119992 (+) 1188 WP_023369088.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35426.29 Da        Isoelectric Point: 5.4744

>NTDB_id=705295 NLY75_RS00740 WP_023369082.1 114101..115051(+) (comYA) [Streptococcus suis T15]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=705295 NLY75_RS00740 WP_023369082.1 114101..115051(+) (comYA) [Streptococcus suis T15]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTACCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCTTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCGGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGATAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCGGGTGTCTAT
GCCCGTATGTTGGAATTGGGGGTCAGCCCTGAGGAGCTAAACAATGCTCTTCAAGGTATTGCCTATCAACGCTTGATCGG
GGGAGGAGGTGTAGTGGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

69.032

98.101

0.677
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361