Detailed information NTG0061641

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: SANR_RS01175
• Genome accession: NC_022239
• Coordinates: 216390..216707 (+)
• Length: 105 a.a.
• NCBI ID: WP_020998068.1
• Uniprot ID: U2XY26
• Organism: Streptococcus anginosus C238
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 211390..221707

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS01145 (SANR_0220)	-	211513..212043 (+)	531	WP_003033434.1	FUSC family protein	-
SANR_RS01150 (SANR_0221)	-	212120..212479 (+)	360	WP_003028467.1	MerR family transcriptional regulator	-
SANR_RS01155 (SANR_0222)	glnA	212518..213864 (+)	1347	WP_003033463.1	type I glutamate--ammonia ligase	-
SANR_RS01160 (SANR_0223)	-	214053..214418 (+)	366	WP_020999445.1	DUF1033 family protein	-
SANR_RS01165 (SANR_0224)	comYA	214488..215429 (+)	942	WP_003033431.1	competence type IV pilus ATPase ComGA	Machinery gene
SANR_RS01170 (SANR_0225)	comYB	215371..216393 (+)	1023	WP_020999446.1	competence type IV pilus assembly protein ComGB	Machinery gene
SANR_RS01175 (SANR_0226)	comYC	216390..216707 (+)	318	WP_020998068.1	competence type IV pilus major pilin ComGC	Machinery gene
SANR_RS01180 (SANR_0227)	comYD	216667..217095 (+)	429	WP_020999411.1	competence type IV pilus minor pilin ComGD	Machinery gene
SANR_RS01185	comGE/cglE	217067..217360 (+)	294	WP_003035318.1	competence type IV pilus minor pilin ComGE	Machinery gene
SANR_RS01190 (SANR_0228)	comGF/cglF	217344..217781 (+)	438	WP_003035329.1	competence type IV pilus minor pilin ComGF	Machinery gene
SANR_RS01195 (SANR_0229)	comGG	217762..218088 (+)	327	WP_020999447.1	competence type IV pilus minor pilin ComGG	-
SANR_RS01200 (SANR_0230)	comYH	218173..219126 (+)	954	WP_003035359.1	class I SAM-dependent methyltransferase	Machinery gene
SANR_RS01205 (SANR_0231)	-	219173..220372 (+)	1200	WP_003035323.1	acetate kinase	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11678.82 Da
• Isoelectric Point: 10.1006

>NTDB_id=61641 SANR_RS01175 WP_020998068.1 216390..216707(+) (comYC) [Streptococcus anginosus C238]
MKKIKNIKVKAFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVSEGT
ITDKQAVSYKAYYAKHTKEARTVAD

Nucleotide

• Length: 318 bp

>NTDB_id=61641 SANR_RS01175 WP_020998068.1 216390..216707(+) (comYC) [Streptococcus anginosus C238]
ATGAAAAAAATTAAAAATATAAAGGTAAAAGCTTTCACTTTGGTAGAAATGTTAGTGGTGCTTCTAATCATCAGTGTTTT
GATGCTTTTGTTTGTTCCGAATTTGACCAAACAAAAAGAAGCTGTAACGGAAAAAGGAAATGCAGCTGTTGTGAAGGTTG
TCGAAAGTCAGGCAGAGCTTTTTGAAGTGAATCATACTAATGAAAAAGCGACGCTTTCAAAATTAGTCAGTGAAGGAACT
ATTACAGACAAGCAAGCAGTATCATACAAGGCTTATTATGCAAAACATACAAAAGAAGCTCGCACAGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: U2XY26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	72.381	100	0.724
comYC	Streptococcus mutans UA140	68.571	100	0.686
comYC	Streptococcus mutans UA159	68.571	100	0.686
comGC/cglC	Streptococcus mitis NCTC 12261	69.608	97.143	0.676
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC	Lactococcus lactis subsp. cremoris KW2	55.769	99.048	0.552
comYC	Streptococcus suis isolate S10	64.045	84.762	0.543