Detailed information NTG0061644

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: SANR_RS01190
• Genome accession: NC_022239
• Coordinates: 217344..217781 (+)
• Length: 145 a.a.
• NCBI ID: WP_003035329.1
• Uniprot ID: F9P803
• Organism: Streptococcus anginosus C238
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 212344..222781

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS01155 (SANR_0222)	glnA	212518..213864 (+)	1347	WP_003033463.1	type I glutamate--ammonia ligase	-
SANR_RS01160 (SANR_0223)	-	214053..214418 (+)	366	WP_020999445.1	DUF1033 family protein	-
SANR_RS01165 (SANR_0224)	comYA	214488..215429 (+)	942	WP_003033431.1	competence type IV pilus ATPase ComGA	Machinery gene
SANR_RS01170 (SANR_0225)	comYB	215371..216393 (+)	1023	WP_020999446.1	competence type IV pilus assembly protein ComGB	Machinery gene
SANR_RS01175 (SANR_0226)	comYC	216390..216707 (+)	318	WP_020998068.1	competence type IV pilus major pilin ComGC	Machinery gene
SANR_RS01180 (SANR_0227)	comYD	216667..217095 (+)	429	WP_020999411.1	competence type IV pilus minor pilin ComGD	Machinery gene
SANR_RS01185	comGE/cglE	217067..217360 (+)	294	WP_003035318.1	competence type IV pilus minor pilin ComGE	Machinery gene
SANR_RS01190 (SANR_0228)	comGF/cglF	217344..217781 (+)	438	WP_003035329.1	competence type IV pilus minor pilin ComGF	Machinery gene
SANR_RS01195 (SANR_0229)	comGG	217762..218088 (+)	327	WP_020999447.1	competence type IV pilus minor pilin ComGG	-
SANR_RS01200 (SANR_0230)	comYH	218173..219126 (+)	954	WP_003035359.1	class I SAM-dependent methyltransferase	Machinery gene
SANR_RS01205 (SANR_0231)	-	219173..220372 (+)	1200	WP_003035323.1	acetate kinase	-
SANR_RS01210 (SANR_0232)	glmS	220762..222576 (+)	1815	WP_020999448.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16865.57 Da
• Isoelectric Point: 10.6422

>NTDB_id=61644 SANR_RS01190 WP_003035329.1 217344..217781(+) (comGF/cglF) [Streptococcus anginosus C238]
MFKANKVKAFTLLEALVALFVISGSVLLFQSMTRLLASEVRARQHSEQREWLLFAHQLEAELIRSSFEKVENNRLYMKQD
GKTIAFGKSSGQDFRKTNANGKGYQPMIYNVKKAEISQKNELIHIRMTFKRGLEREFVYRVETKS

Nucleotide

• Length: 438 bp

>NTDB_id=61644 SANR_RS01190 WP_003035329.1 217344..217781(+) (comGF/cglF) [Streptococcus anginosus C238]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACACTTTTAGAGGCTCTGGTTGCCCTCTTTGTAATCAGCGGGAGTGTGCT
ATTATTTCAATCGATGACGCGTCTTCTGGCTTCGGAGGTCCGAGCTCGACAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCCCATCAATTAGAAGCGGAATTGATTCGTTCTTCATTTGAAAAAGTGGAGAATAATCGTTTATACATGAAGCAGGAC
GGTAAGACGATTGCATTTGGAAAGTCAAGTGGACAAGATTTCAGAAAAACCAATGCAAATGGGAAAGGCTATCAGCCTAT
GATTTATAATGTGAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATATCAGAATGACATTTAAGCGAGGATTGG
AAAGGGAGTTCGTCTATCGTGTGGAAACAAAGAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

3D structure

• AlphaFold DB: F9P803

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae R6	66.429	96.552	0.641
comGF/cglF	Streptococcus pneumoniae TIGR4	66.429	96.552	0.641
comGF/cglF	Streptococcus pneumoniae Rx1	66.429	96.552	0.641
comGF/cglF	Streptococcus pneumoniae D39	66.429	96.552	0.641
comGF/cglF	Streptococcus mitis NCTC 12261	65.714	96.552	0.634
comGF/cglF	Streptococcus mitis SK321	65.714	96.552	0.634
comYF	Streptococcus mutans UA159	43.972	97.241	0.428
comYF	Streptococcus mutans UA140	43.972	97.241	0.428
comGF	Lactococcus lactis subsp. cremoris KW2	42.963	93.103	0.4