Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SANR_RS01165 Genome accession   NC_022239
Coordinates   214488..215429 (+) Length   313 a.a.
NCBI ID   WP_003033431.1    Uniprot ID   I0SLG1
Organism   Streptococcus anginosus C238     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 209488..220429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS01140 (SANR_0219) - 209799..210998 (+) 1200 WP_003033487.1 phosphoglycerate kinase -
  SANR_RS01145 (SANR_0220) - 211513..212043 (+) 531 WP_003033434.1 FUSC family protein -
  SANR_RS01150 (SANR_0221) - 212120..212479 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  SANR_RS01155 (SANR_0222) glnA 212518..213864 (+) 1347 WP_003033463.1 type I glutamate--ammonia ligase -
  SANR_RS01160 (SANR_0223) - 214053..214418 (+) 366 WP_020999445.1 DUF1033 family protein -
  SANR_RS01165 (SANR_0224) comYA 214488..215429 (+) 942 WP_003033431.1 competence type IV pilus ATPase ComGA Machinery gene
  SANR_RS01170 (SANR_0225) comYB 215371..216393 (+) 1023 WP_020999446.1 competence type IV pilus assembly protein ComGB Machinery gene
  SANR_RS01175 (SANR_0226) comYC 216390..216707 (+) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  SANR_RS01180 (SANR_0227) comYD 216667..217095 (+) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  SANR_RS01185 comGE/cglE 217067..217360 (+) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  SANR_RS01190 (SANR_0228) comGF/cglF 217344..217781 (+) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  SANR_RS01195 (SANR_0229) comGG 217762..218088 (+) 327 WP_020999447.1 competence type IV pilus minor pilin ComGG -
  SANR_RS01200 (SANR_0230) comYH 218173..219126 (+) 954 WP_003035359.1 class I SAM-dependent methyltransferase Machinery gene
  SANR_RS01205 (SANR_0231) - 219173..220372 (+) 1200 WP_003035323.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35955.09 Da        Isoelectric Point: 6.2451

>NTDB_id=61639 SANR_RS01165 WP_003033431.1 214488..215429(+) (comYA) [Streptococcus anginosus C238]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWYTQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFADQQ
IMSIEDPVEIKQSGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKVVLQGICYQRLIAKGGIVDFVSERYQEHEPIDWNRQIDQLHAAGHINLEQAESEKIIHG

Nucleotide


Download         Length: 942 bp        

>NTDB_id=61639 SANR_RS01165 WP_003033431.1 214488..215429(+) (comYA) [Streptococcus anginosus C238]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTCAAGTTTACCGCTGGGATGAATGTCGGCGAAAAACGTAGAAGCCAGCTAGGATCTTGTGATTATCAA
TATGGTGATAAGAAAACGTCATTACGACTGTCAACAGTGGGGGATTATCGCGGATATGAAAGTCTAGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGTTGAAGTTTTGGTATACTCAGATTCCAGAGCTGAAAGAACGTTTCAAACAGCGAGGACTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGAAAAACGACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCGATCAGCAA
ATCATGTCCATTGAAGACCCTGTTGAAATCAAGCAGTCTGGCATGTTACAGCTGCAACTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTGACAGGAGTGACTGTCTTTTCAACCATTCATGCAAAAAGCGTACGAGGTGTTTAT
GAACGGTTGCTAGAATTGGGAGTGACAGAAGCCGAGCTGAAAGTTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAACACGAGCCAATCGATTGGAATCGACAGATTGATCAGC
TTCATGCAGCAGGACATATCAATCTTGAACAAGCAGAATCGGAAAAAATTATCCACGGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SLG1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

82.903

99.042

0.821
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.806

99.042

0.751
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.484

99.042

0.748
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.484

99.042

0.748
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.484

99.042

0.748
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.484

99.042

0.748
  comYA Streptococcus mutans UA159

63.666

99.361

0.633
  comYA Streptococcus mutans UA140

63.666

99.361

0.633
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

54.019

99.361

0.537
  comGA Latilactobacillus sakei subsp. sakei 23K

43.542

86.581

0.377

Multiple sequence alignment