Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SANR_RS01185 Genome accession   NC_022239
Coordinates   217067..217360 (+) Length   97 a.a.
NCBI ID   WP_003035318.1    Uniprot ID   I0SGQ0
Organism   Streptococcus anginosus C238     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 212067..222360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS01150 (SANR_0221) - 212120..212479 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  SANR_RS01155 (SANR_0222) glnA 212518..213864 (+) 1347 WP_003033463.1 type I glutamate--ammonia ligase -
  SANR_RS01160 (SANR_0223) - 214053..214418 (+) 366 WP_020999445.1 DUF1033 family protein -
  SANR_RS01165 (SANR_0224) comYA 214488..215429 (+) 942 WP_003033431.1 competence type IV pilus ATPase ComGA Machinery gene
  SANR_RS01170 (SANR_0225) comYB 215371..216393 (+) 1023 WP_020999446.1 competence type IV pilus assembly protein ComGB Machinery gene
  SANR_RS01175 (SANR_0226) comYC 216390..216707 (+) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  SANR_RS01180 (SANR_0227) comYD 216667..217095 (+) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  SANR_RS01185 comGE/cglE 217067..217360 (+) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  SANR_RS01190 (SANR_0228) comGF/cglF 217344..217781 (+) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  SANR_RS01195 (SANR_0229) comGG 217762..218088 (+) 327 WP_020999447.1 competence type IV pilus minor pilin ComGG -
  SANR_RS01200 (SANR_0230) comYH 218173..219126 (+) 954 WP_003035359.1 class I SAM-dependent methyltransferase Machinery gene
  SANR_RS01205 (SANR_0231) - 219173..220372 (+) 1200 WP_003035323.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10936.85 Da        Isoelectric Point: 10.4707

>NTDB_id=61643 SANR_RS01185 WP_003035318.1 217067..217360(+) (comGE/cglE) [Streptococcus anginosus C238]
MENLRKQYVRGTILLEALLASAVFAFIVTLLLGQIHQSRQTENDLLKKEEVLRVANMALQTKQSHLTINGIEVRVKKSQQ
GIQIYHGKELIVGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=61643 SANR_RS01185 WP_003035318.1 217067..217360(+) (comGE/cglE) [Streptococcus anginosus C238]
ATGGAAAATTTAAGAAAACAATACGTTAGAGGAACGATTTTATTAGAAGCTTTATTGGCATCGGCTGTTTTTGCGTTTAT
TGTGACCTTGTTATTGGGGCAGATCCATCAGTCTCGACAGACAGAAAATGATTTACTGAAAAAAGAAGAAGTTCTAAGAG
TGGCTAATATGGCATTACAAACAAAGCAAAGCCATTTAACAATAAACGGTATTGAAGTTCGTGTTAAAAAAAGTCAACAA
GGCATCCAGATTTATCATGGGAAGGAGCTGATTGTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SGQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

42.424

100

0.433
  comYE Streptococcus mutans UA159

42.424

100

0.433

Multiple sequence alignment