Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   KV238_RS02005 Genome accession   NZ_CP078012
Coordinates   400280..400765 (-) Length   161 a.a.
NCBI ID   WP_014623459.1    Uniprot ID   A0A6D2L510
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_18-036     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 395280..405765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KV238_RS01980 (KV238_01975) - 395711..396271 (-) 561 WP_230923746.1 TIGR01440 family protein -
  KV238_RS01985 (KV238_01980) - 396284..396757 (-) 474 WP_042671321.1 ECF transporter S component -
  KV238_RS01990 (KV238_01985) - 396763..397512 (-) 750 WP_043026574.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  KV238_RS01995 (KV238_01990) truA 397502..398251 (-) 750 WP_165622810.1 tRNA pseudouridine(38-40) synthase TruA -
  KV238_RS02000 (KV238_01995) - 398438..399802 (+) 1365 WP_165622809.1 aspartate kinase -
  KV238_RS02005 (KV238_02000) comX/sigX/comX2/sigX2 400280..400765 (-) 486 WP_014623459.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 161 a.a.        Molecular weight: 19403.39 Da        Isoelectric Point: 8.2702

>NTDB_id=586240 KV238_RS02005 WP_014623459.1 400280..400765(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MTDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGSVGHAIPAGGLGVDDYVAYQLIVKEVEERLTESELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide


Download         Length: 486 bp        

>NTDB_id=586240 KV238_RS02005 WP_014623459.1 400280..400765(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGACTGATGATTTAGTGAGGTTGTTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGGCGGTTGATCTTGTATCGGTTATTGGTCACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTATATCGTTATTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGTCGGTAGGCCATGCGATACCAGCAGGTGGTTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCGATTGACAGAGAGTGAGCTGTCGCAGTTTCGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGTGAG
AAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6D2L510

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

67.5

99.379

0.671
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

67.5

99.379

0.671
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

67.5

99.379

0.671
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

67.5

99.379

0.671
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

70.395

94.41

0.665
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

70.395

94.41

0.665
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

47.742

96.273

0.46
  comX/sigX Streptococcus mutans UA159

46.497

97.516

0.453
  comX Streptococcus sobrinus strain NIDR 6715-7

45.752

95.031

0.435
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

40.667

93.168

0.379
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

40.397

93.789

0.379
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

40.397

93.789

0.379
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.333

93.168

0.366
  comX/comX2 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

38.667

93.168

0.36
  comX Streptococcus thermophilus LMG 18311

37.908

95.031

0.36
  comX Streptococcus thermophilus LMD-9

37.908

95.031

0.36