Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   I6L86_RS04460 Genome accession   NZ_CP077259
Coordinates   964784..965263 (+) Length   159 a.a.
NCBI ID   WP_000471940.1    Uniprot ID   A0AAX2L348
Organism   Streptococcus mitis strain FDAARGOS 1456     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 959784..970263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L86_RS04435 (I6L86_04435) - 960526..961401 (-) 876 WP_004238891.1 RluA family pseudouridine synthase -
  I6L86_RS04440 (I6L86_04440) pbp2a 961488..963683 (+) 2196 WP_000762651.1 penicillin-binding protein PBP2A -
  I6L86_RS04445 (I6L86_04445) rpmG 963736..963888 (+) 153 WP_001809375.1 50S ribosomal protein L33 -
  I6L86_RS04450 (I6L86_04450) secE 963898..964074 (+) 177 WP_001210990.1 preprotein translocase subunit SecE -
  I6L86_RS04455 (I6L86_04455) nusG 964128..964664 (+) 537 WP_000376740.1 transcription termination/antitermination protein NusG -
  I6L86_RS04460 (I6L86_04460) comX/sigX/comX2/sigX2 964784..965263 (+) 480 WP_000471940.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 20103.81 Da        Isoelectric Point: 7.1188

>NTDB_id=580377 I6L86_RS04460 WP_000471940.1 964784..965263(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis strain FDAARGOS 1456]
MFKELYEEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEELVEDIPRLRKYFKTKFRNRILDHIRKQESQKRR
YDKEPYEEVGEISHRISEGGMWLDEYYLFHETLRDYRNKQSKDKQEELERVLRHERFRGRQRVLRDLRIVFKEFDIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=580377 I6L86_RS04460 WP_000471940.1 964784..965263(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis strain FDAARGOS 1456]
ATGTTTAAAGAATTATATGAAGAAGTCCAAGGAATTGTATACAAGTGTAGAAATGAATATTACCTTCATTTATGGGAGCT
ATCAGATTGGGACCAAGAGGGAATGATTTGCTTACATGAATTGATCAGTAGAGAAGAAGAGCTAGTAGAAGATATTCCTC
GTTTACGTAAATACTTCAAAACTAAATTCCGTAATCGAATTTTAGACCATATCCGTAAACAAGAAAGCCAGAAGCGTAGA
TATGATAAAGAACCCTATGAAGAAGTAGGTGAGATTAGTCATCGTATCAGTGAGGGAGGTATGTGGCTAGATGAGTATTA
TCTCTTTCATGAGACACTAAGAGATTATAGAAACAAACAAAGTAAAGACAAACAAGAAGAGTTAGAACGCGTCTTAAGAC
ATGAACGCTTCCGAGGGCGTCAAAGAGTATTGAGAGACTTACGTATTGTGTTTAAGGAGTTTGATATCCGTACTCATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

100

100

1
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

97.484

100

0.975
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

94.34

100

0.943
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

94.304

99.371

0.937
  comX/comX2 Streptococcus pneumoniae R6

92.453

100

0.925
  comX/comX1 Streptococcus pneumoniae R6

92.453

100

0.925
  comX/comX2 Streptococcus pneumoniae D39

92.453

100

0.925
  comX/comX2 Streptococcus pneumoniae Rx1

92.453

100

0.925
  comX/comX1 Streptococcus pneumoniae Rx1

92.453

100

0.925
  comX/comX1 Streptococcus pneumoniae D39

92.453

100

0.925
  comX/comX2 Streptococcus pneumoniae TIGR4

91.824

100

0.918
  comX/comX1 Streptococcus pneumoniae TIGR4

91.824

100

0.918
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.359

98.113

0.484
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.359

98.113

0.484
  comX/sigX Streptococcus mutans UA159

47.712

96.226

0.459
  comX/sigX Streptococcus suis D9

45.752

96.226

0.44
  comX/sigX Streptococcus suis isolate S10

45.752

96.226

0.44
  comX/sigX Streptococcus suis P1/7

45.752

96.226

0.44
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.282

93.711

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.282

93.711

0.396
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

41.447

95.597

0.396
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

41.447

95.597

0.396
  comX Streptococcus sobrinus strain NIDR 6715-7

37.662

96.855

0.365
  comX Streptococcus salivarius SK126

37.419

97.484

0.365