Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   I2437_RS01295 Genome accession   NZ_CP065061
Coordinates   244293..244778 (+) Length   161 a.a.
NCBI ID   WP_012677392.1    Uniprot ID   A0A380JSU6
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ33     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 239293..249778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2437_RS01295 (IEMOCGPF_00256) comX/sigX/comX2/sigX2 244293..244778 (+) 486 WP_012677392.1 hypothetical protein Regulator
  I2437_RS01300 (IEMOCGPF_00257) - 245237..246601 (-) 1365 WP_012680116.1 aspartate kinase -
  I2437_RS01305 (IEMOCGPF_00258) truA 246788..247537 (+) 750 WP_012677362.1 tRNA pseudouridine(38-40) synthase TruA -
  I2437_RS01310 (IEMOCGPF_00259) - 247527..248276 (+) 750 WP_012677363.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  I2437_RS01315 (IEMOCGPF_00260) - 248282..248755 (+) 474 WP_159334804.1 ECF transporter S component -
  I2437_RS01320 (IEMOCGPF_00261) - 248768..249328 (+) 561 WP_206157897.1 TIGR01440 family protein -

Sequence

Protein


Download         Length: 161 a.a.        Molecular weight: 19371.39 Da        Isoelectric Point: 7.3119

>NTDB_id=506580 I2437_RS01295 WP_012677392.1 244293..244778(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MSDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGAVGHAIPAGGLGVDDYVAYQLIVKEVEEQLTESELLQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide


Download         Length: 486 bp        

>NTDB_id=506580 I2437_RS01295 WP_012677392.1 244293..244778(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGAGTGATGATTTAGTGAGGTTATTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGACGGTTGATCTTGTATCGGTTGTTGGTTACTTATCCAGAATTGATAGAAG
ATGAGGAGAAGCTGTACCGTTATTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGGCGGTAGGCCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCAATTGACAGAGAGCGAGCTGTTACAGTTTAGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGTGAG
AAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JSU6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

68.75

99.379

0.683
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

68.75

99.379

0.683
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

68.75

99.379

0.683
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

68.75

99.379

0.683
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

68.75

99.379

0.683
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

68.75

99.379

0.683
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.387

96.273

0.466
  comX/sigX Streptococcus mutans UA159

46.497

97.516

0.453
  comX Streptococcus sobrinus strain NIDR 6715-7

45.752

95.031

0.435
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

40.667

93.168

0.379
  comX Streptococcus thermophilus LMD-9

39.216

95.031

0.373
  comX Streptococcus thermophilus LMG 18311

39.216

95.031

0.373
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

39.735

93.789

0.373
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

39.735

93.789

0.373
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.333

93.168

0.366
  comX/comX2 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

38.667

93.168

0.36