Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   I2436_RS08295 Genome accession   NZ_CP065060
Coordinates   1757265..1757750 (-) Length   161 a.a.
NCBI ID   WP_111678543.1    Uniprot ID   A0AAX2LGZ2
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1752265..1762750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS08260 (GDAKBCAL_01655) - 1752612..1753373 (-) 762 WP_284730085.1 class I SAM-dependent methyltransferase -
  I2436_RS08265 (GDAKBCAL_01656) rsfS 1753485..1753838 (-) 354 WP_021321124.1 ribosome silencing factor -
  I2436_RS08270 (GDAKBCAL_01657) yqeK 1753840..1754433 (-) 594 WP_021321125.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  I2436_RS08275 (GDAKBCAL_01658) - 1754430..1755062 (-) 633 WP_021321126.1 nicotinate-nucleotide adenylyltransferase -
  I2436_RS08280 (GDAKBCAL_01659) yhbY 1755146..1755454 (-) 309 WP_012516273.1 ribosome assembly RNA-binding protein YhbY -
  I2436_RS08285 (GDAKBCAL_01660) yqeH 1755481..1756599 (-) 1119 WP_012516274.1 ribosome biogenesis GTPase YqeH -
  I2436_RS08290 (GDAKBCAL_01661) - 1756599..1757126 (-) 528 WP_024273233.1 YqeG family HAD IIIA-type phosphatase -
  I2436_RS08295 (GDAKBCAL_01662) comX/sigX/comX2/sigX2 1757265..1757750 (-) 486 WP_111678543.1 competence protein ComX Regulator

Sequence

Protein


Download         Length: 161 a.a.        Molecular weight: 19385.42 Da        Isoelectric Point: 7.3119

>NTDB_id=506563 I2436_RS08295 WP_111678543.1 1757265..1757750(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MTDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGAVGHAIPAGGLGVDDYVAYQLIVKEVEEQLTESELLQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide


Download         Length: 486 bp        

>NTDB_id=506563 I2436_RS08295 WP_111678543.1 1757265..1757750(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGACTGATGATTTAGTGAGGTTATTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTGGATGATTGGTTACAGGAGGGACGGTTGATCTTGTATCGGTTGTTGGTTACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTGTACCGTTACTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGGCTGTAGGCCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCAATTGACAGAGAGCGAGCTGTTACAGTTTAGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGATTTTACTGGTGAG
AAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

68.125

99.379

0.677
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

68.125

99.379

0.677
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

68.125

99.379

0.677
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

68.125

99.379

0.677
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

68.125

99.379

0.677
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

68.125

99.379

0.677
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.387

96.273

0.466
  comX/sigX Streptococcus mutans UA159

46.497

97.516

0.453
  comX Streptococcus sobrinus strain NIDR 6715-7

45.752

95.031

0.435
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

40.667

93.168

0.379
  comX Streptococcus thermophilus LMD-9

39.216

95.031

0.373
  comX Streptococcus thermophilus LMG 18311

39.216

95.031

0.373
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

39.735

93.789

0.373
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

39.735

93.789

0.373
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.333

93.168

0.366
  comX/comX2 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

38.667

93.168

0.36