Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   MSA_RS04500 Genome accession   NC_021486
Coordinates   804296..804949 (+) Length   217 a.a.
NCBI ID   WP_016480646.1    Uniprot ID   -
Organism   Streptococcus agalactiae ILRI005     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 799296..809949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MSA_RS04475 (MSA_9210) - 799464..800294 (+) 831 WP_000735512.1 MetQ/NlpA family ABC transporter substrate-binding protein -
  MSA_RS04480 (MSA_9220) - 800529..802115 (+) 1587 WP_016480644.1 DEAD/DEAH box helicase -
  MSA_RS04485 (MSA_9230) - 802300..802566 (-) 267 WP_000598736.1 GIY-YIG nuclease family protein -
  MSA_RS04490 (MSA_9240) - 802559..803323 (-) 765 WP_000567428.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  MSA_RS04495 (MSA_9250) - 803458..804198 (+) 741 WP_016480645.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  MSA_RS04500 (MSA_9260) comEA/celA/cilE 804296..804949 (+) 654 WP_016480646.1 helix-hairpin-helix domain-containing protein Machinery gene
  MSA_RS04505 (MSA_9270) comEC/celB 804933..807170 (+) 2238 WP_016480647.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MSA_RS04510 (MSA_9280) - 807296..808105 (+) 810 WP_016480648.1 Cof-type HAD-IIB family hydrolase -
  MSA_RS04515 (MSA_9290) - 808116..809060 (+) 945 WP_016480649.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23684.07 Da        Isoelectric Point: 9.5543

>NTDB_id=49078 MSA_RS04500 WP_016480646.1 804296..804949(+) (comEA/celA/cilE) [Streptococcus agalactiae ILRI005]
MFEIVLEKIKSHKWETTGIIVGLLLFGILGLNHFGTHHKVDDLNINLEKKVSTITEKKVPMISHVKDKVSNQVTVDVKGA
VNHPGVYSLPSQSRVTDAIKRAGGLSNLADSKSVNLAQKLQDETVIYVAQKGEKITVVEEEKANNIATQGNSKGKINLNK
ADLSSLQTISGVGAKRAQDILDYRDSQGGFKTIDDLKNVSGIGEKTLEKLRQDVTID

Nucleotide


Download         Length: 654 bp        

>NTDB_id=49078 MSA_RS04500 WP_016480646.1 804296..804949(+) (comEA/celA/cilE) [Streptococcus agalactiae ILRI005]
ATGTTTGAAATAGTATTGGAAAAAATTAAATCGCATAAATGGGAGACAACAGGAATTATTGTAGGACTCTTATTATTTGG
AATTTTGGGTTTAAATCATTTTGGCACTCATCATAAAGTAGACGATTTAAATATCAATTTAGAGAAAAAAGTATCAACTA
TAACAGAAAAAAAGGTACCAATGATTAGTCACGTCAAAGATAAAGTATCTAATCAAGTAACGGTTGACGTAAAAGGGGCA
GTCAATCATCCAGGTGTTTATAGTTTGCCTTCTCAAAGTCGTGTAACAGATGCGATTAAGCGTGCAGGTGGACTAAGCAA
TCTCGCTGATAGTAAATCCGTTAATCTAGCACAGAAATTACAAGATGAGACGGTTATCTATGTTGCTCAAAAAGGTGAAA
AAATAACTGTTGTGGAAGAGGAGAAAGCAAATAATATCGCCACTCAGGGAAATAGTAAGGGGAAAATTAATCTTAATAAA
GCAGATTTATCAAGTCTTCAGACCATATCAGGCGTTGGAGCTAAAAGAGCTCAAGATATTTTAGATTATCGTGATAGTCA
AGGTGGTTTTAAAACTATTGATGACCTCAAAAATGTATCAGGTATTGGTGAGAAAACACTAGAAAAATTACGTCAAGATG
TTACAATTGACTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(153-215)

SLBB domain (SLBB)

(75-128)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis SK321

44.091

100

0.447
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

43.891

100

0.447
  comEA/celA/cilE Streptococcus pneumoniae Rx1

42.986

100

0.438
  comEA/celA/cilE Streptococcus pneumoniae D39

42.986

100

0.438
  comEA/celA/cilE Streptococcus pneumoniae R6

42.986

100

0.438
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.534

100

0.433
  comEA Lactococcus lactis subsp. cremoris KW2

39.462

100

0.406
  comEA Streptococcus thermophilus LMD-9

54.545

70.968

0.387

Multiple sequence alignment