Detailed information NTG0463258

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: HW271_RS08130
• Genome accession: NZ_CP058258
• Coordinates: 1649426..1649905 (-)
• Length: 159 a.a.
• NCBI ID: WP_178895559.1
• Uniprot ID: A0A7H8ZA27
• Organism: Streptococcus sp. oral taxon 061 strain F0704
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1644426..1654905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HW271_RS08130 (HW271_08130)	comR/comR2	1649426..1649905 (-)	480	WP_178895559.1	sigma factor	Regulator
HW271_RS08135 (HW271_08135)	pbp2a	1650088..1652313 (-)	2226	WP_178895560.1	penicillin-binding protein PBP2A	-
HW271_RS08140 (HW271_08140)	-	1652402..1653280 (+)	879	WP_302851393.1	RluA family pseudouridine synthase	-
HW271_RS08145 (HW271_08145)	gap	1653353..1654363 (-)	1011	WP_006154814.1	type I glyceraldehyde-3-phosphate dehydrogenase	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19420.33 Da
• Isoelectric Point: 8.8520

>NTDB_id=463258 HW271_RS08130 WP_178895559.1 1649426..1649905(-) (comR/comR2) [Streptococcus sp. oral taxon 061 strain F0704]
MLEMNYQEVKAIVHKCRKEYYLHLWEKEDWDQEGMICLHELLENHPDFKGNKNKEFYTYFKTKFRNRILDAVRKQESYKR
RLDRQAYEEVSEISHRLGEGGLLIDESYALQEMLKEYRAGLGKERLELFERLLADERFKGRKAMLKELKHVLRDFSPKR

Nucleotide

• Length: 480 bp

>NTDB_id=463258 HW271_RS08130 WP_178895559.1 1649426..1649905(-) (comR/comR2) [Streptococcus sp. oral taxon 061 strain F0704]
ATGTTAGAAATGAATTACCAAGAAGTGAAAGCTATTGTACACAAATGTAGAAAAGAATACTACCTTCATTTATGGGAAAA
AGAAGATTGGGATCAAGAGGGAATGATTTGCCTACATGAATTATTAGAAAATCACCCTGATTTCAAGGGAAATAAAAATA
AGGAATTTTATACCTACTTCAAAACAAAGTTTCGAAATCGAATTTTGGATGCAGTTAGGAAACAAGAAAGTTATAAAAGA
AGATTGGATCGACAAGCTTATGAAGAAGTGAGCGAAATTAGCCATCGATTAGGCGAAGGGGGGCTGTTGATAGATGAGTC
TTACGCATTACAAGAAATGCTTAAAGAGTATCGAGCAGGGTTAGGAAAAGAAAGGTTGGAGTTGTTTGAACGCTTGTTAG
CTGATGAGCGATTCAAAGGAAGAAAAGCAATGTTGAAAGAACTAAAGCATGTGCTAAGAGATTTTTCTCCAAAAAGATAA

Domains

Predicted by InterproScan.

• Sigma-70 region 2 (Sigma70_r2) (2-77)

3D structure

• AlphaFold DB: A0A7H8ZA27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	57.516	96.226	0.553
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	57.516	96.226	0.553
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	53.797	99.371	0.535
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	53.797	99.371	0.535
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	53.165	99.371	0.528
comX/comX2	Streptococcus pneumoniae D39	52.532	99.371	0.522
comX/comX1	Streptococcus pneumoniae D39	52.532	99.371	0.522
comX/comX2	Streptococcus pneumoniae R6	52.532	99.371	0.522
comX/comX1	Streptococcus pneumoniae R6	52.532	99.371	0.522
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	52.532	99.371	0.522
comX/comX2	Streptococcus pneumoniae Rx1	52.532	99.371	0.522
comX/comX1	Streptococcus pneumoniae Rx1	52.532	99.371	0.522
comX/comX1	Streptococcus pneumoniae TIGR4	51.899	99.371	0.516
comX/comX2	Streptococcus pneumoniae TIGR4	51.899	99.371	0.516
comX/sigX	Streptococcus mutans UA159	47.771	98.742	0.472
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.57	99.371	0.453
comX/sigX	Streptococcus suis D9	45.333	94.34	0.428
comX/sigX	Streptococcus suis isolate S10	45.333	94.34	0.428
comX/sigX	Streptococcus suis P1/7	45.333	94.34	0.428
comX/sigX	Streptococcus salivarius strain HSISS4	42.763	95.597	0.409
comX	Streptococcus salivarius SK126	42.763	95.597	0.409
comX	Streptococcus sobrinus strain NIDR 6715-7	41.333	94.34	0.39
comX	Streptococcus thermophilus LMG 18311	40.789	95.597	0.39
comX	Streptococcus thermophilus LMD-9	40.789	95.597	0.39