Detailed information NTG0401492

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: GKC13_RS00865
• Genome accession: NZ_CP046134
• Coordinates: 154764..155090 (+)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain MAG_rmk202_sterm
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 149764..160090

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GKC13_RS00850 (GKC13_00845)	-	152401..152763 (+)	363	WP_011226630.1	DUF1033 family protein	-
GKC13_RS00855 (GKC13_00850)	comGA/cglA/cilD	152844..153785 (+)	942	WP_071417491.1	competence type IV pilus ATPase ComGA	Machinery gene
GKC13_RS00860 (GKC13_00855)	comYB	153667..154767 (+)	1101	WP_207560111.1	competence type IV pilus assembly protein ComGB	Machinery gene
GKC13_RS00865 (GKC13_00860)	comYC	154764..155090 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
GKC13_RS00870 (GKC13_00865)	comYD	155050..155478 (+)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
GKC13_RS00875 (GKC13_00870)	comGE	155450..155743 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
GKC13_RS00880 (GKC13_00875)	comYF	155727..156164 (+)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
GKC13_RS00885 (GKC13_00880)	comGG	156142..156459 (+)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
GKC13_RS00890 (GKC13_00885)	comYH	156504..157469 (+)	966	WP_208301810.1	class I SAM-dependent methyltransferase	Machinery gene
GKC13_RS00895 (GKC13_00890)	-	157515..158708 (+)	1194	WP_014608740.1	acetate kinase	-
GKC13_RS00900 (GKC13_00895)	-	158957..159154 (+)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
GKC13_RS09810 (GKC13_00900)	-	159397..159822 (+)	426	WP_087010196.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=401492 GKC13_RS00865 WP_002946126.1 154764..155090(+) (comYC) [Streptococcus thermophilus strain MAG_rmk202_sterm]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=401492 GKC13_RS00865 WP_002946126.1 154764..155090(+) (comYC) [Streptococcus thermophilus strain MAG_rmk202_sterm]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361