Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   GFB63_RS03400 Genome accession   NZ_CP045596
Coordinates   669222..669548 (-) Length   108 a.a.
NCBI ID   WP_002946126.1    Uniprot ID   A0A0E2Q1B3
Organism   Streptococcus thermophilus strain TK-P3A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 664222..674548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS10520 (GFB63_03450) - 664488..664826 (-) 339 WP_228024408.1 CPBP family intramembrane glutamic endopeptidase -
  GFB63_RS10525 (GFB63_03455) - 664870..665145 (-) 276 WP_084826166.1 CAAX protease -
  GFB63_RS03365 (GFB63_03460) - 665157..665354 (-) 198 WP_084826167.1 helix-turn-helix transcriptional regulator -
  GFB63_RS03370 (GFB63_03465) - 665603..666796 (-) 1194 WP_084826168.1 acetate kinase -
  GFB63_RS03375 (GFB63_03470) comYH 666852..667808 (-) 957 WP_023909974.1 class I SAM-dependent methyltransferase Machinery gene
  GFB63_RS03380 (GFB63_03475) comGG 667853..668170 (-) 318 WP_023909975.1 competence type IV pilus minor pilin ComGG -
  GFB63_RS03385 (GFB63_03480) comYF 668148..668585 (-) 438 WP_084829135.1 competence type IV pilus minor pilin ComGF Machinery gene
  GFB63_RS03390 (GFB63_03485) comGE 668569..668862 (-) 294 WP_084829136.1 competence type IV pilus minor pilin ComGE -
  GFB63_RS03395 (GFB63_03490) comYD 668834..669262 (-) 429 WP_171815055.1 competence type IV pilus minor pilin ComGD Machinery gene
  GFB63_RS03400 (GFB63_03495) comYC 669222..669548 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  GFB63_RS03405 (GFB63_03500) comYB 669545..670645 (-) 1101 WP_144239090.1 competence type IV pilus assembly protein ComGB Machinery gene
  GFB63_RS03410 (GFB63_03505) comYA 670527..671468 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  GFB63_RS03415 (GFB63_03510) - 671549..671911 (-) 363 WP_023909982.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 11914.00 Da        Isoelectric Point: 9.9219

>NTDB_id=395462 GFB63_RS03400 WP_002946126.1 669222..669548(-) (comYC) [Streptococcus thermophilus strain TK-P3A]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=395462 GFB63_RS03400 WP_002946126.1 669222..669548(-) (comYC) [Streptococcus thermophilus strain TK-P3A]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q1B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus mutans UA140

69.231

96.296

0.667
  comYC Streptococcus mutans UA159

69.231

96.296

0.667
  comYC Streptococcus gordonii str. Challis substr. CH1

63.81

97.222

0.62
  comGC/cglC Streptococcus mitis SK321

62.264

98.148

0.611
  comGC/cglC Streptococcus mitis NCTC 12261

58.333

100

0.583
  comGC/cglC Streptococcus pneumoniae D39

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae R6

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae Rx1

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae TIGR4

58.491

98.148

0.574
  comGC Lactococcus lactis subsp. cremoris KW2

56.604

98.148

0.556
  comYC Streptococcus suis isolate S10

60.227

81.481

0.491
  comGC Staphylococcus aureus MW2

50

72.222

0.361
  comGC Staphylococcus aureus N315

50

72.222

0.361

Multiple sequence alignment